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BIOMARKER:
PLK1 overexpression
i
Other names:
PLK1, Polo Like Kinase 1, Serine/Threonine-Protein Kinase PLK1, Serine/Threonine-Protein Kinase 13, Polo-Like Kinase 1, STPK13, PLK-1, Cell Cycle Regulated Protein Kinase, Polo-Like Kinase (Drosophila), Polo (Drosophia)-Like Kinase
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Entrez ID:
5347
Related biomarkers:
Expression
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PLK1 overexpression
Hormone Receptor Positive Breast Cancer
PLK1 overexpression
Hormone Receptor Positive Breast Cancer
palbociclib
Resistant: B - Late Trials
palbociclib
Resistant
:
B
palbociclib
Resistant: B - Late Trials
palbociclib
Resistant
:
B
PLK1 overexpression
Renal Cell Carcinoma
PLK1 overexpression
Renal Cell Carcinoma
sunitinib
Resistant: C3 – Early Trials
sunitinib
Resistant
:
C3
sunitinib
Resistant: C3 – Early Trials
sunitinib
Resistant
:
C3
PLK1 overexpression
Colorectal Cancer
PLK1 overexpression
Colorectal Cancer
Immunotherapy + PLK1 inhibitor
Sensitive: D – Preclinical
Immunotherapy + PLK1 inhibitor
Sensitive
:
D
Immunotherapy + PLK1 inhibitor
Sensitive: D – Preclinical
Immunotherapy + PLK1 inhibitor
Sensitive
:
D
PLK1 overexpression
Estrogen Receptor Positive Breast Cancer
PLK1 overexpression
Estrogen Receptor Positive Breast Cancer
anastrozole
Sensitive: D – Preclinical
anastrozole
Sensitive
:
D
anastrozole
Sensitive: D – Preclinical
anastrozole
Sensitive
:
D
PLK1 overexpression
Lung Cancer
PLK1 overexpression
Lung Cancer
trametinib + pralsetinib
Sensitive: D – Preclinical
trametinib + pralsetinib
Sensitive
:
D
trametinib + pralsetinib
Sensitive: D – Preclinical
trametinib + pralsetinib
Sensitive
:
D
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