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BIOMARKER:

PAK4 overexpression

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Other names: PAK4, P21 (RAC1) Activated Kinase 4, P21 Protein (Cdc42/Rac)-Activated Kinase 4, Serine/Threonine-Protein Kinase PAK 4, P21(CDKN1A)-Activated Kinase 4, Protein Kinase Related To S. Cerevisiae STE20, Effector For Cdc42Hs, P21-Activated Kinase 4
Entrez ID:
Related biomarkers:
PAK4 overexpression
Solid Tumor
PD1 inhibitor
Resistant: C3 – Early Trials
PAK4 overexpression
Melanoma
vemurafenib
Resistant: D – Preclinical
PAK4 overexpression
Solid Tumor
KPT-9274 + PD1 inhibitor
Sensitive: D – Preclinical