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BIOMARKER:

NOTCH2 mutation

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Entrez ID:

Related biomarkers:

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BCL6 fusion + NOTCH2 mutation (1)

NOTCH2-NTRK1 fusion + EGFR L858R (1)

BCL6 fusion + NOTCH2 mutation (1)

NOTCH2-NTRK1 fusion + EGFR L858R (1)

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NOTCH2 mutation	Non Small Cell Lung Cancer	NOTCH2 mutation	Non Small Cell Lung Cancer	tislelizumab-jsgr Sensitive: B - Late Trials tislelizumab-jsgr Sensitive : B	tislelizumab-jsgr Sensitive: B - Late Trials tislelizumab-jsgr Sensitive : B
NOTCH2 mutation	Non Small Cell Lung Cancer	NOTCH2 mutation	Non Small Cell Lung Cancer	Immunotherapy Sensitive: C3 – Early Trials Immunotherapy Sensitive : C3	Immunotherapy Sensitive: C3 – Early Trials Immunotherapy Sensitive : C3
NOTCH2 mutation	Diffuse Large B Cell Lymphoma	NOTCH2 mutation	Diffuse Large B Cell Lymphoma	Resistant: C3 – Early Trials Resistant : C3	Resistant: C3 – Early Trials Resistant : C3
NOTCH2 mutation	Triple Negative Breast Cancer	NOTCH2 mutation	Triple Negative Breast Cancer	nirogacestat Sensitive: D – Preclinical nirogacestat Sensitive : D	nirogacestat Sensitive: D – Preclinical nirogacestat Sensitive : D