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BIOMARKER:
NOTCH2 mutation
i
Other names:
NOTCH2, Notch Receptor 2, Notch 2, Neurogenic Locus Notch Homolog Protein 2, Notch (Drosophila) Homolog 2, Notch Homolog 2, AGS2
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Entrez ID:
4853
Related biomarkers:
Mutation
Fusion
Others
‹
NOTCH2-NTRK1 fusion (0)
NOTCH2-NTRK1 fusion (0)
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Associations
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Trials
VERI cancer hierarchy
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NOTCH2 mutation
Non Small Cell Lung Cancer
NOTCH2 mutation
Non Small Cell Lung Cancer
tislelizumab-jsgr
Sensitive: B - Late Trials
tislelizumab-jsgr
Sensitive
:
B
tislelizumab-jsgr
Sensitive: B - Late Trials
tislelizumab-jsgr
Sensitive
:
B
NOTCH2 mutation
Non Small Cell Lung Cancer
NOTCH2 mutation
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
NOTCH2 mutation
Diffuse Large B Cell Lymphoma
NOTCH2 mutation
Diffuse Large B Cell Lymphoma
Resistant: C3 – Early Trials
Resistant
:
C3
Resistant: C3 – Early Trials
Resistant
:
C3
NOTCH2 mutation
Triple Negative Breast Cancer
NOTCH2 mutation
Triple Negative Breast Cancer
nirogacestat
Sensitive: D – Preclinical
nirogacestat
Sensitive
:
D
nirogacestat
Sensitive: D – Preclinical
nirogacestat
Sensitive
:
D
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