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BIOMARKER:

NOTCH1 mutation

i
Other names: NOTCH1, TAN1
Entrez ID:
Related biomarkers:
NOTCH1 mutation
CLL
ofatumumab
Resistant: B - Late Trials
NOTCH1 mutation
CLL
obinutuzumab
Resistant: B - Late Trials
NOTCH1 mutation
NSCLC
Immunotherapy
Sensitive: C3 – Early Trials
NOTCH1 mutation
CLL
ibrutinib
Resistant: C3 – Early Trials
NOTCH1 mutation
T Acute Lymphoblastic Leukemia
prednisone
Sensitive: C3 – Early Trials
NOTCH1 mutation
Prolymphocytic Leukemia
ibrutinib
Resistant: C3 – Early Trials
NOTCH1 mutation
Mantle Cell Lymphoma
ibrutinib
Resistant: C3 – Early Trials
NOTCH1 mutation
Diffuse Large B Cell Lymphoma
zanubrutinib
Sensitive: C3 – Early Trials
NOTCH1 mutation
Diffuse Large B Cell Lymphoma
rituximab
Sensitive: C3 – Early Trials
NOTCH1 mutation
CRC
sintilimab + fruquintinib
Resistant: C3 – Early Trials
NOTCH1 mutation
Adenoid Cystic Carcinoma
tretinoin
Sensitive: C3 – Early Trials
NOTCH1 mutation
Mantle Cell Lymphoma
Compound E
Sensitive: D – Preclinical
NOTCH1 mutation
Triple Negative Breast Cancer
PF-03084014
Sensitive: D – Preclinical
NOTCH1 mutation
SCCHN
WNT974
Sensitive: D – Preclinical
NOTCH1 mutation
T Acute Lymphoblastic Leukemia
CB-839
Sensitive: D – Preclinical
NOTCH1 mutation
T Acute Lymphoblastic Leukemia
IACS-010759
Sensitive: D – Preclinical