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GENE:

NFKB1 (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1)

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FusionPlex™ Pan-Heme panel

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NFKB1 overexpression	Melanoma	NFKB1 overexpression	Melanoma	PD1 inhibitor Resistant: C3 – Early Trials PD1 inhibitor Resistant : C3	PD1 inhibitor Resistant: C3 – Early Trials PD1 inhibitor Resistant : C3
NFKB1 expression	Esophageal Squamous Cell Carcinoma	NFKB1 expression	Esophageal Squamous Cell Carcinoma	rivoceranib Sensitive: C3 – Early Trials rivoceranib Sensitive : C3	rivoceranib Sensitive: C3 – Early Trials rivoceranib Sensitive : C3
NFKB1 overexpression	Acute Myelogenous Leukemia	NFKB1 overexpression	Acute Myelogenous Leukemia	cytarabine + doxorubicin hydrochloride Resistant: C3 – Early Trials cytarabine + doxorubicin hydrochloride Resistant : C3	cytarabine + doxorubicin hydrochloride Resistant: C3 – Early Trials cytarabine + doxorubicin hydrochloride Resistant : C3
NFKB1 expression	Gastric Cancer	NFKB1 expression	Gastric Cancer	BBI608 Sensitive: D – Preclinical BBI608 Sensitive : D	BBI608 Sensitive: D – Preclinical BBI608 Sensitive : D
NFKB1 overexpression	Pancreatic Cancer	NFKB1 overexpression	Pancreatic Cancer	albumin-bound paclitaxel Resistant: D – Preclinical albumin-bound paclitaxel Resistant : D	albumin-bound paclitaxel Resistant: D – Preclinical albumin-bound paclitaxel Resistant : D