^
NTRK1 fusion
Neurofibrosarcoma
entrectinib
Sensitive
:
C1
NTRK3 fusion
Neurofibrosarcoma
entrectinib
Sensitive
:
C1
BRAF V600E
Neurofibrosarcoma
vemurafenib
Sensitive
:
C1
NF2 E108X
Neurofibrosarcoma
everolimus
Resistant
:
C3
NF2 E108X
Neurofibrosarcoma
temsirolimus
Sensitive
:
C3
TSC2 A736V
Neurofibrosarcoma
everolimus
Resistant
:
C3
TSC2 A736V
Neurofibrosarcoma
temsirolimus
Sensitive
:
C3
TJP1-ROS1 fusion + NF1 mutation
Neurofibrosarcoma
crizotinib
Resistant
:
C4
NF1 mutation
Neurofibrosarcoma
DR6MP + JHU395
Sensitive
:
D
NF1 mutation
Neurofibrosarcoma
DR6MP
Sensitive
:
D
NF1 mutation
Neurofibrosarcoma
MEK inhibitor + c-MET inhibitor
Sensitive
:
D
TP53 mutation
Neurofibrosarcoma
AZD1775
Sensitive
:
D