^
No biomarker
Ewing Sarcoma
dactinomycin
Sensitive
:
A1
No biomarker
Ewing Sarcoma
IE
Sensitive
:
A2
No biomarker
Ewing Sarcoma
VC
Sensitive
:
A2
No biomarker
Ewing Sarcoma
GT
Sensitive
:
A2
No biomarker
Ewing Sarcoma
melphalan + busulfan
Sensitive
:
A2
No biomarker
Ewing Sarcoma
ifosfamide + cyclophosphamide + etoposide IV + topotecan
Sensitive
:
A2
No biomarker
Ewing Sarcoma
temozolomide + irinotecan
Sensitive
:
A2
No biomarker
Ewing Sarcoma
temozolomide + irinotecan + vincristine
Sensitive
:
A2
No biomarker
Ewing Sarcoma
cyclophosphamide + topotecan
Sensitive
:
A2
No biomarker
Ewing Sarcoma
carboplatin + ifosfamide + etoposide IV
Sensitive
:
A2
No biomarker
Ewing Sarcoma
gemcitabine + docetaxel
Sensitive
:
A2
No biomarker
Ewing Sarcoma
cabozantinib tablet
Sensitive
:
A2
TMB-H
Ewing Sarcoma
pembrolizumab
Sensitive
:
A2
MSI-H/dMMR
Ewing Sarcoma
pembrolizumab
Sensitive
:
A2
No biomarker
Ewing Sarcoma
VIDE
Sensitive
:
A2
No biomarker
Ewing Sarcoma
VAI
Sensitive
:
A2
No biomarker
Ewing Sarcoma
VDC
Sensitive
:
A2
No biomarker
Ewing Sarcoma
SP2577
Sensitive
:
B
No biomarker
Ewing Sarcoma
ONCT-216
Sensitive
:
B
MGMT promoter methylation
Ewing Sarcoma
temozolomide + irinotecan
Sensitive
:
C2
IGF1R underexpression
Ewing Sarcoma
mTOR inhibitor + IGF-1R inhibitor
Sensitive
:
C3
IGF1 elevation
Ewing Sarcoma
CP-751,871
Sensitive
:
C3
PTPRD R995C
Ewing Sarcoma
mTOR inhibitor + IGF-1R inhibitor
Sensitive
:
C3
PTPRD V253I + PTPRD W775stop
Ewing Sarcoma
mTOR inhibitor + IGF-1R inhibitor
Sensitive
:
C3
PTPRD V253I + PTPRD W775stop
Ewing Sarcoma
IGF-1R inhibitor
Sensitive
:
C3
SPARC overexpression
Ewing Sarcoma
albumin-bound paclitaxel
Sensitive
:
C3
B4GALNT1 expression
Ewing Sarcoma
dinutuximab beta
Sensitive
:
C3
EWSR1-FLI1 fusion
Ewing Sarcoma
VDC
Sensitive
:
C4
FGFR3 amplification + FGFR4 amplification + FLT4 amplification
Ewing Sarcoma
trametinib + pazopanib
Resistant
:
C4
CD99 positive + VIM positive
Ewing Sarcoma
OPEC
Sensitive
:
C4
IGF1R expression
Ewing Sarcoma
IGF-1R inhibitor
Sensitive
:
D
EWSR1-FLI1 fusion
Ewing Sarcoma
CDK12 inhibitor
Sensitive
:
D