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BIOMARKER:
MET mutation
i
Other names:
DFNB97, AUTS9, RCCP2, C-Met, HGFR, HGF Receptor, Met Proto-Oncogene, HGF/SF Receptor, Proto-Oncogene C-Met, Scatter Factor Receptor, Tyrosine-Protein Kinase Met, Hepatocyte Growth Factor Receptor, MET, MET Proto-Oncogene, Receptor Tyrosine Kinase
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Entrez ID:
4233
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
MET overexpression (32)
MET expression (12)
MET positive (8)
EGFR expression + MET expression (2)
MET overexpression + KDR overexpression (2)
MET overexpression + SYK overexpression (2)
TPBG expression + MET expression (2)
FGFR overexpression + MET overexpression (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
MET overexpression + MUC5B overexpression (1)
MET underexpression (1)
PTGS2 positive + MET positive + TOPK positive + EGFR mutation (0)
MET overexpression (32)
MET expression (12)
MET positive (8)
EGFR expression + MET expression (2)
MET overexpression + KDR overexpression (2)
MET overexpression + SYK overexpression (2)
TPBG expression + MET expression (2)
FGFR overexpression + MET overexpression (1)
MET expression + HER-2 expression (1)
MET overexpression + HER-2 overexpression (1)
MET overexpression + MUC5B overexpression (1)
MET underexpression (1)
PTGS2 positive + MET positive + TOPK positive + EGFR mutation (0)
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MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
savolitinib
Sensitive: B - Late Trials
savolitinib
Sensitive
:
B
savolitinib
Sensitive: B - Late Trials
savolitinib
Sensitive
:
B
MET mutation
Gastric Cancer
MET mutation
Gastric Cancer
TPX-0022
Sensitive: C2 – Inclusion Criteria
TPX-0022
Sensitive
:
C2
TPX-0022
Sensitive: C2 – Inclusion Criteria
TPX-0022
Sensitive
:
C2
MET mutation
Non Small Cell Lung Cancer
MET mutation
Non Small Cell Lung Cancer
crizotinib
Sensitive: C2 – Inclusion Criteria
crizotinib
Sensitive
:
C2
crizotinib
Sensitive: C2 – Inclusion Criteria
crizotinib
Sensitive
:
C2
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
cabozantinib capsule
Sensitive: C2 – Inclusion Criteria
cabozantinib capsule
Sensitive
:
C2
cabozantinib capsule
Sensitive: C2 – Inclusion Criteria
cabozantinib capsule
Sensitive
:
C2
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
crizotinib
Sensitive: C2 – Inclusion Criteria
crizotinib
Sensitive
:
C2
crizotinib
Sensitive: C2 – Inclusion Criteria
crizotinib
Sensitive
:
C2
MET mutation
Non Small Cell Lung Cancer
MET mutation
Non Small Cell Lung Cancer
MGCD265
Sensitive: C2 – Inclusion Criteria
MGCD265
Sensitive
:
C2
MGCD265
Sensitive: C2 – Inclusion Criteria
MGCD265
Sensitive
:
C2
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
c-MET inhibitor
Sensitive: C3 – Early Trials
c-MET inhibitor
Sensitive
:
C3
c-MET inhibitor
Sensitive: C3 – Early Trials
c-MET inhibitor
Sensitive
:
C3
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
everolimus
Sensitive: C3 – Early Trials
everolimus
Sensitive
:
C3
everolimus
Sensitive: C3 – Early Trials
everolimus
Sensitive
:
C3
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
GSK1363089
Sensitive: C3 – Early Trials
GSK1363089
Sensitive
:
C3
GSK1363089
Sensitive: C3 – Early Trials
GSK1363089
Sensitive
:
C3
MET mutation
Non Small Cell Lung Cancer
MET mutation
Non Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
MET mutation
Renal Cell Carcinoma
MET mutation
Renal Cell Carcinoma
durvalumab + savolitinib
Sensitive: C3 – Early Trials
durvalumab + savolitinib
Sensitive
:
C3
durvalumab + savolitinib
Sensitive: C3 – Early Trials
durvalumab + savolitinib
Sensitive
:
C3
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