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Association details:
Biomarker:
MET mutation
Cancer:
Renal Cell Carcinoma
Drug:
sunitinib
(
c-KIT inhibitor
,
VEGFR inhibitor
,
PDGFR inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
ASCO 2020
Title:
MET status and treatment outcomes in papillary renal cell carcinoma (PRCC): Pooled analysis of historical data.
Published date:
05/28/2020
Excerpt:
In sunitinib-treated pts, PFS and TTF were numerically longer in pts with MET-driven tumors vs pts with MET-ind tumors, but OS was similar (Table)
DOI:
10.1200/JCO.2020.38.15_suppl.e19321
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