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BIOMARKER:
KRAS G12
i
Other names:
KRAS, KRAS1, KRAS2, Kirsten rat sarcoma viral oncogene homolog
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Entrez ID:
3845
Related biomarkers:
Expression
Mutation
CNA
Others
‹
KRAS amplification (7)
KRAS deletion (1)
KRAS amplification (7)
KRAS deletion (1)
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Associations
News
Trials
VERI cancer hierarchy
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KRAS G12
Colorectal Cancer
KRAS G12
Colorectal Cancer
cetuximab
Resistant: A1 - Approval
cetuximab
Resistant
:
A1
cetuximab
Resistant: A1 - Approval
cetuximab
Resistant
:
A1
KRAS G12
Colorectal Cancer
KRAS G12
Colorectal Cancer
trifluridine/tipiracil
Resistant: B - Late Trials
trifluridine / tipiracil
Resistant
:
B
trifluridine/tipiracil
Resistant: B - Late Trials
trifluridine / tipiracil
Resistant
:
B
KRAS G12
Ovarian Cancer
KRAS G12
Ovarian Cancer
cetuximab
Resistant: C1 - Off-label
cetuximab
Resistant
:
C1
cetuximab
Resistant: C1 - Off-label
cetuximab
Resistant
:
C1
KRAS G12
Non Small Cell Lung Cancer
KRAS G12
Non Small Cell Lung Cancer
RMC-6236
Sensitive: C2 – Inclusion Criteria
RMC-6236
Sensitive
:
C2
RMC-6236
Sensitive: C2 – Inclusion Criteria
RMC-6236
Sensitive
:
C2
KRAS G12
Colorectal Cancer
KRAS G12
Colorectal Cancer
bevacizumab
Sensitive: C3 – Early Trials
bevacizumab
Sensitive
:
C3
bevacizumab
Sensitive: C3 – Early Trials
bevacizumab
Sensitive
:
C3
KRAS G12
Colorectal Cancer
KRAS G12
Colorectal Cancer
AZD1775
Sensitive: C3 – Early Trials
AZD1775
Sensitive
:
C3
AZD1775
Sensitive: C3 – Early Trials
AZD1775
Sensitive
:
C3
KRAS G12
Pancreatic Ductal Adenocarcinoma
KRAS G12
Pancreatic Ductal Adenocarcinoma
RMC-6236
Sensitive: C3 – Early Trials
RMC-6236
Sensitive
:
C3
RMC-6236
Sensitive: C3 – Early Trials
RMC-6236
Sensitive
:
C3
KRAS G12
Colorectal Cancer
KRAS G12
Colorectal Cancer
RTB101
Sensitive: D – Preclinical
RTB101
Sensitive
:
D
RTB101
Sensitive: D – Preclinical
RTB101
Sensitive
:
D
KRAS G12
Colorectal Cancer
KRAS G12
Colorectal Cancer
selumetinib + RTB101
Sensitive: D – Preclinical
selumetinib + RTB101
Sensitive
:
D
selumetinib + RTB101
Sensitive: D – Preclinical
selumetinib + RTB101
Sensitive
:
D
KRAS G12
Colorectal Cancer
KRAS G12
Colorectal Cancer
selumetinib
Sensitive: D – Preclinical
selumetinib
Sensitive
:
D
selumetinib
Sensitive: D – Preclinical
selumetinib
Sensitive
:
D
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