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BIOMARKER:
KIT exon 11 mutation
i
Other names:
KIT, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Entrez ID:
3815
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
KIT mutation (32)
KIT exon 9 mutation (9)
KIT N822K (7)
KIT D816V (6)
KIT exon 13 mutation (6)
KIT exon 17 mutation (6)
KIT L576P (5)
KIT T670I (4)
KIT D820Y (3)
KIT K642E (3)
KIT V559D (3)
KIT V654A (3)
KIT wild-type (3)
KIT S628N (2)
KIT W557_V559delinsF (2)
KIT exon 11 mutation + KIT exon 17 mutation (2)
KIT exon 18 mutation (2)
KIT exon 8 mutation (2)
BRAF G466V + KIT K509Q (1)
KDR Q472H + KIT M541L (1)
KIT A829P (1)
KIT D816G (1)
KIT D816H (1)
KIT D818Y (1)
KIT D820A (1)
KIT D820G (1)
KIT L576 (1)
KIT M541L (1)
KIT M552_V555delMYEV (1)
KIT N820Y (1)
KIT N822Y (1)
KIT V559A + KIT N822I (1)
KIT V559_E561del (1)
KIT V560E (1)
KIT V560G (1)
KIT W557_V559>C (1)
KIT W557_V559>F (1)
KIT Y823D (1)
KIT exon 11 W557_K558delins (1)
KIT exon 14 mutation (1)
KIT exon 17 mutation + KIT exon 18 mutation (1)
KIT translocation (1)
NR4A3 rearrangement + KIT mutation (1)
KIT D820E (0)
KIT K509Q (0)
KIT N822I (0)
KIT V559 (0)
KIT V559A (0)
KIT V560D (0)
KIT W557 (0)
KIT rs3733542 (0)
KIT mutation (32)
KIT exon 9 mutation (9)
KIT N822K (7)
KIT D816V (6)
KIT exon 13 mutation (6)
KIT exon 17 mutation (6)
KIT L576P (5)
KIT T670I (4)
KIT D820Y (3)
KIT K642E (3)
KIT V559D (3)
KIT V654A (3)
KIT wild-type (3)
KIT S628N (2)
KIT W557_V559delinsF (2)
KIT exon 11 mutation + KIT exon 17 mutation (2)
KIT exon 18 mutation (2)
KIT exon 8 mutation (2)
BRAF G466V + KIT K509Q (1)
KDR Q472H + KIT M541L (1)
KIT A829P (1)
KIT D816G (1)
KIT D816H (1)
KIT D818Y (1)
KIT D820A (1)
KIT D820G (1)
KIT L576 (1)
KIT M541L (1)
KIT M552_V555delMYEV (1)
KIT N820Y (1)
KIT N822Y (1)
KIT V559A + KIT N822I (1)
KIT V559_E561del (1)
KIT V560E (1)
KIT V560G (1)
KIT W557_V559>C (1)
KIT W557_V559>F (1)
KIT Y823D (1)
KIT exon 11 W557_K558delins (1)
KIT exon 14 mutation (1)
KIT exon 17 mutation + KIT exon 18 mutation (1)
KIT translocation (1)
NR4A3 rearrangement + KIT mutation (1)
KIT D820E (0)
KIT K509Q (0)
KIT N822I (0)
KIT V559 (0)
KIT V559A (0)
KIT V560D (0)
KIT W557 (0)
KIT rs3733542 (0)
›
Associations
News
Trials
VERI cancer hierarchy
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KIT exon 11 mutation
Gastric Cancer
KIT exon 11 mutation
Gastric Cancer
imatinib
Sensitive: B - Late Trials
imatinib
Sensitive
:
B
imatinib
Sensitive: B - Late Trials
imatinib
Sensitive
:
B
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
ripretinib
Sensitive: B - Late Trials
ripretinib
Sensitive
:
B
ripretinib
Sensitive: B - Late Trials
ripretinib
Sensitive
:
B
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
regorafenib
Sensitive: B - Late Trials
regorafenib
Sensitive
:
B
regorafenib
Sensitive: B - Late Trials
regorafenib
Sensitive
:
B
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
imatinib
Sensitive: C2 – Inclusion Criteria
imatinib
Sensitive
:
C2
imatinib
Sensitive: C2 – Inclusion Criteria
imatinib
Sensitive
:
C2
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
nilotinib
Sensitive: C2 – Inclusion Criteria
nilotinib
Sensitive
:
C2
nilotinib
Sensitive: C2 – Inclusion Criteria
nilotinib
Sensitive
:
C2
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
ponatinib
Sensitive: C2 – Inclusion Criteria
ponatinib
Sensitive
:
C2
ponatinib
Sensitive: C2 – Inclusion Criteria
ponatinib
Sensitive
:
C2
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
imatinib
Sensitive: C3 – Early Trials
imatinib
Sensitive
:
C3
imatinib
Sensitive: C3 – Early Trials
imatinib
Sensitive
:
C3
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
nilotinib
Sensitive: C3 – Early Trials
nilotinib
Sensitive
:
C3
nilotinib
Sensitive: C3 – Early Trials
nilotinib
Sensitive
:
C3
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
sunitinib
Sensitive: C3 – Early Trials
sunitinib
Sensitive
:
C3
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
anlotinib
Sensitive: C3 – Early Trials
anlotinib
Sensitive
:
C3
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
KIT exon 11 mutation
Gastrointestinal Stromal Tumor
avapritinib
Resistant: C4 – Case Studies
avapritinib
Resistant
:
C4
avapritinib
Resistant: C4 – Case Studies
avapritinib
Resistant
:
C4
KIT exon 11 mutation
Melanoma
KIT exon 11 mutation
Melanoma
dasatinib
Resistant: C4 – Case Studies
dasatinib
Resistant
:
C4
dasatinib
Resistant: C4 – Case Studies
dasatinib
Resistant
:
C4
^
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