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BIOMARKER:

IFNG overexpression

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IFNG expression (4)

IFNG expression (4)

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IFNG overexpression	Melanoma	IFNG overexpression	Melanoma	PD1 inhibitor Sensitive: C3 – Early Trials PD1 inhibitor Sensitive : C3	PD1 inhibitor Sensitive: C3 – Early Trials PD1 inhibitor Sensitive : C3
IFNG overexpression	Non Small Cell Lung Cancer	IFNG overexpression	Non Small Cell Lung Cancer	nivolumab Sensitive: C3 – Early Trials nivolumab Sensitive : C3	nivolumab Sensitive: C3 – Early Trials nivolumab Sensitive : C3
IFNG overexpression	Squamous Cell Carcinoma of Head and Neck	IFNG overexpression	Squamous Cell Carcinoma of Head and Neck	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3	pembrolizumab Sensitive: C3 – Early Trials pembrolizumab Sensitive : C3
IFNG overexpression	Biliary Tract Cancer	IFNG overexpression	Biliary Tract Cancer	sintilimab Sensitive: C3 – Early Trials sintilimab Sensitive : C3	sintilimab Sensitive: C3 – Early Trials sintilimab Sensitive : C3
IFNG overexpression	Esophageal Squamous Cell Carcinoma	IFNG overexpression	Esophageal Squamous Cell Carcinoma	toripalimab-tpzi Sensitive: C3 – Early Trials toripalimab-tpzi Sensitive : C3	toripalimab-tpzi Sensitive: C3 – Early Trials toripalimab-tpzi Sensitive : C3
IFNG overexpression	Pancreatic Cancer	IFNG overexpression	Pancreatic Cancer	anlotinib + penpulimab Sensitive: C3 – Early Trials anlotinib + penpulimab Sensitive : C3	anlotinib + penpulimab Sensitive: C3 – Early Trials anlotinib + penpulimab Sensitive : C3