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Association details:
| Biomarker: | IFNG overexpression |
|---|---|
| Cancer: | Melanoma |
| Drug Class: | PD1 inhibitor |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients
Published date:
10/19/2020
Excerpt:
We collected at baseline peripheral blood samples from 18 consecutive advanced melanoma patients treated with anti-PD-1 therapy...We found that IFN-γ mRNA expression levels were significantly higher in responder patients compared to non-responder ones.
DOI:
10.1038/s41598-020-72711-2
