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BIOMARKER:

IDH1 wild-type + NF1 mutation

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Entrez ID:

Related biomarkers:

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IDH1 mutation (79)

NF1 mutation (24)

IDH wild-type (3)

FLT3-ITD mutation + IDH1 mutation (2)

IDH1 wild-type + BRAF mutation (2)

BRAF mutation + NF1 mutation (2)

EGFR mutation + TP53 mutation + NF1 mutation (2)

DNMT3A mutation + IDH mutation (1)

EGFR L858R + IDH1 R132C (1)

EGFR mutation + IDH1 mutation (1)

EGFR mutation+ IDH1 R132H (1)

FLT3 mutation + IDH1 mutation (1)

IDH1 R132C + EGFR L861Q (1)

IDH1 R132C + IDH1 S280F (1)

IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)

IDH1 R132H + PTEN C78T (1)

IDH1 mutation + TP53 mutation (1)

IDH1 rs1437410 (1)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)

NF1 2195G>T (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

NF1 rearrangement (1)

NF1 mutation (1)

SDHB mutation + NF1 mutation (1)

IDH mutation + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) (0)

IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)

IDH mutation + NTRK fusion (0)

NF1 7806+2T>C (0)

NF1 L581Ffs*6 (0)

IDH1 mutation (79)

NF1 mutation (24)

IDH wild-type (3)

FLT3-ITD mutation + IDH1 mutation (2)

IDH1 wild-type + BRAF mutation (2)

BRAF mutation + NF1 mutation (2)

EGFR mutation + TP53 mutation + NF1 mutation (2)

DNMT3A mutation + IDH mutation (1)

EGFR L858R + IDH1 R132C (1)

EGFR mutation + IDH1 mutation (1)

EGFR mutation+ IDH1 R132H (1)

FLT3 mutation + IDH1 mutation (1)

IDH1 R132C + EGFR L861Q (1)

IDH1 R132C + IDH1 S280F (1)

IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)

IDH1 R132H + PTEN C78T (1)

IDH1 mutation + TP53 mutation (1)

IDH1 rs1437410 (1)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)

NF1 2195G>T (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

NF1 rearrangement (1)

NF1 mutation (1)

SDHB mutation + NF1 mutation (1)

IDH mutation + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) (0)

IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)

IDH mutation + NTRK fusion (0)

NF1 7806+2T>C (0)

NF1 L581Ffs*6 (0)

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IDH1 wild-type + NF1 mutation	Glioma	IDH1 wild-type + NF1 mutation	Glioma	trametinib Sensitive: C3 – Early Trials trametinib Sensitive : C3	trametinib Sensitive: C3 – Early Trials trametinib Sensitive : C3
IDH1 wild-type + NF1 mutation	Glioma	IDH1 wild-type + NF1 mutation	Glioma	trametinib + dabrafenib Sensitive: C3 – Early Trials trametinib + dabrafenib Sensitive : C3	trametinib + dabrafenib Sensitive: C3 – Early Trials trametinib + dabrafenib Sensitive : C3