Associations - NF1 mutation

BIOMARKER:

NF1 mutation

Entrez ID:

4763

Related biomarkers:

Expression

Mutation

CNA

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NF1 mutation NF1 mutation	CNS Tumor CNS Tumor	selumetinib Sensitive: C3 – Early Trials selumetinib Sensitive : C3
NF1 mutation NF1 mutation	Glioma Glioma	trametinib Sensitive: C3 – Early Trials trametinib Sensitive : C3
NF1 mutation NF1 mutation	Melanoma Melanoma	vemurafenib Resistant: C3 – Early Trials vemurafenib Resistant : C3
NF1 mutation NF1 mutation	Thyroid Gland Anaplastic Carcinoma Thyroid Gland Anaplastic Carcinoma	atezolizumab + cobimetinib Sensitive: C3 – Early Trials atezolizumab + cobimetinib Sensitive : C3
NF1 mutation NF1 mutation	Colorectal Cancer CRC	AZD6738 Sensitive: C3 – Early Trials AZD6738 Sensitive : C3
NF1 mutation NF1 mutation	Multiple Myeloma Multiple Myeloma	MEK inhibitor Sensitive: C3 – Early Trials MEK inhibitor Sensitive : C3
NF1 mutation NF1 mutation	Thyroid Gland Medullary Carcinoma Thyroid Gland Medullary Carcinoma	vandetanib Sensitive: C4 – Case Studies vandetanib Sensitive : C4
NF1 mutation NF1 mutation	Sarcoma Sarcoma	SAR442720 Sensitive: C4 – Case Studies SAR442720 Sensitive : C4
NF1 mutation NF1 mutation	Melanoma Melanoma	VTX-11e Resistant: D – Preclinical VTX-11e Resistant : D
NF1 mutation NF1 mutation	Melanoma Melanoma	PD-0325901 Sensitive: D – Preclinical PD-0325901 Sensitive : D
NF1 mutation NF1 mutation	Neurofibrosarcoma Neurofibrosarcoma	DR6MP + JHU395 Sensitive: D – Preclinical DR6MP + JHU395 Sensitive : D
NF1 mutation NF1 mutation	Neurofibrosarcoma Neurofibrosarcoma	DR6MP Sensitive: D – Preclinical DR6MP Sensitive : D