^
BIOMARKER:

NF1 mutation

i
Other names: NFNS, NF1, Neurofibromin 1, Neurofibromatosis-Related Protein NF-1, Truncated Neurofibromin 1
Entrez ID:
Related biomarkers:
NF1 mutation
CNS Tumor
selumetinib
Sensitive: C3 – Early Trials
NF1 mutation
Glioma
trametinib
Sensitive: C3 – Early Trials
NF1 mutation
Melanoma
vemurafenib
Resistant: C3 – Early Trials
NF1 mutation
Thyroid Gland Anaplastic Carcinoma
atezolizumab + cobimetinib
Sensitive: C3 – Early Trials
NF1 mutation
CRC
AZD6738
Sensitive: C3 – Early Trials
NF1 mutation
Multiple Myeloma
MEK inhibitor
Sensitive: C3 – Early Trials
NF1 mutation
Solid Tumor
selumetinib
Resistant: C3 – Early Trials
NF1 mutation
Melanoma
Immunotherapy
Sensitive: C3 – Early Trials
NF1 mutation
Thyroid Gland Medullary Carcinoma
vandetanib
Sensitive: C4 – Case Studies
NF1 mutation
Sarcoma
SAR442720
Sensitive: C4 – Case Studies
NF1 mutation
Melanoma
VTX-11e
Resistant: D – Preclinical
NF1 mutation
Melanoma
PD-0325901
Sensitive: D – Preclinical
NF1 mutation
Neurofibrosarcoma
DR6MP + JHU395
Sensitive: D – Preclinical
NF1 mutation
Neurofibrosarcoma
DR6MP
Sensitive: D – Preclinical
NF1 mutation
Neurofibrosarcoma
MEK inhibitor + c-MET inhibitor
Sensitive: D – Preclinical