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BIOMARKER:
HR positive
i
Other names:
ESR1, Era, ESR, NR3A1, ER, ER beta, PGR, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, NR3C3
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Entrez ID:
2099
;
5241
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ER positive (199)
HR negative (25)
ER negative (13)
ER positive + PGR positive (12)
PGR positive (10)
HR positive + HER-2 negative (5)
ER expression (3)
ER overexpression (3)
IRF8 overexpression + ER negative (3)
ER positive + HER-2 negative (2)
ER positive + PGR negative (2)
FGFR1 overexpression + HR positive (2)
HR negative + PD-L1 expression (2)
HR positive + ER overexpression (2)
HR positive + HER-2 underexpression (2)
PGR expression (2)
PGR overexpression (2)
AR positive + ER positive (1)
CETN2 overexpression + HR positive (1)
CETN2 overexpression + MLH3 overexpression + PCNA overexpression + HR positive (1)
CTSD positive + ER positive (1)
ER negative + HER-2 negative (1)
ER positive + CDK6 overexpression (1)
ER positive + PGR negative + HER-2 negative (1)
ER underexpression (1)
HDC overexpression + HR positive (1)
HER-2 underexpression + ER underexpression (1)
HR overexpression (1)
HR positive + AR positive (1)
HR positive + BRCA positive (1)
HR positive + CCNE1 overexpression (1)
HR positive + ERBB3 overexpression (1)
HR positive + ERBB3 underexpression (1)
HR positive + HER-2 positive (1)
HR positive + PD-L1 expression (1)
HR positive + PLK1 overexpression (1)
HR positive + TNFRSF11A overexpression (1)
MLH3 overexpression + HR positive (1)
NOTCH3 expression + ER positive + PGR positive (1)
PCNA overexpression + HR positive (1)
PD-L1 overexpression + ER positive (1)
RAD51 overexpression + HR positive (1)
RFC3 overexpression + ER positive (1)
TFF1 overexpression + ER positive (1)
TFF3 overexpression + ER positive (1)
TNFRSF1A overexpression + HR positive (1)
TYMS overexpression + HR positive (1)
PGR negative (1)
BIN3 expression + ER positive (0)
CCNA2 expression + ER positive (0)
CCNB2 expression + ER positive (0)
CTDSP1 expression + ER positive (0)
EPRS1 expression + ER positive (0)
ER negative + HER-2 positive (0)
ER negative + PGR positive (0)
ER positive + HER-2 positive (0)
ER positive + PGR positive + HER-2 positive (0)
FOXD1 expression + ER positive (0)
FTO expression + ER positive (0)
HER-2 negative + AR positive + ER positive (0)
HER-2 negative + ER positive (0)
HR negative + HER-2 positive (0)
MIEN1 expression + ER negative + PR negative (0)
NCOR2 overexpression + ER positive (0)
RBPMS expression + ER positive (0)
SLBP expression + ER positive (0)
WSB2 expression + ER positive (0)
HER-2 negative + PGR positive (0)
PGR positive + HER-2 positive (0)
ER positive (199)
HR negative (25)
ER negative (13)
ER positive + PGR positive (12)
PGR positive (10)
HR positive + HER-2 negative (5)
ER expression (3)
ER overexpression (3)
IRF8 overexpression + ER negative (3)
ER positive + HER-2 negative (2)
ER positive + PGR negative (2)
FGFR1 overexpression + HR positive (2)
HR negative + PD-L1 expression (2)
HR positive + ER overexpression (2)
HR positive + HER-2 underexpression (2)
PGR expression (2)
PGR overexpression (2)
AR positive + ER positive (1)
CETN2 overexpression + HR positive (1)
CETN2 overexpression + MLH3 overexpression + PCNA overexpression + HR positive (1)
CTSD positive + ER positive (1)
ER negative + HER-2 negative (1)
ER positive + CDK6 overexpression (1)
ER positive + PGR negative + HER-2 negative (1)
ER underexpression (1)
HDC overexpression + HR positive (1)
HER-2 underexpression + ER underexpression (1)
HR overexpression (1)
HR positive + AR positive (1)
HR positive + BRCA positive (1)
HR positive + CCNE1 overexpression (1)
HR positive + ERBB3 overexpression (1)
HR positive + ERBB3 underexpression (1)
HR positive + HER-2 positive (1)
HR positive + PD-L1 expression (1)
HR positive + PLK1 overexpression (1)
HR positive + TNFRSF11A overexpression (1)
MLH3 overexpression + HR positive (1)
NOTCH3 expression + ER positive + PGR positive (1)
PCNA overexpression + HR positive (1)
PD-L1 overexpression + ER positive (1)
RAD51 overexpression + HR positive (1)
RFC3 overexpression + ER positive (1)
TFF1 overexpression + ER positive (1)
TFF3 overexpression + ER positive (1)
TNFRSF1A overexpression + HR positive (1)
TYMS overexpression + HR positive (1)
PGR negative (1)
BIN3 expression + ER positive (0)
CCNA2 expression + ER positive (0)
CCNB2 expression + ER positive (0)
CTDSP1 expression + ER positive (0)
EPRS1 expression + ER positive (0)
ER negative + HER-2 positive (0)
ER negative + PGR positive (0)
ER positive + HER-2 positive (0)
ER positive + PGR positive + HER-2 positive (0)
FOXD1 expression + ER positive (0)
FTO expression + ER positive (0)
HER-2 negative + AR positive + ER positive (0)
HER-2 negative + ER positive (0)
HR negative + HER-2 positive (0)
MIEN1 expression + ER negative + PR negative (0)
NCOR2 overexpression + ER positive (0)
RBPMS expression + ER positive (0)
SLBP expression + ER positive (0)
WSB2 expression + ER positive (0)
HER-2 negative + PGR positive (0)
PGR positive + HER-2 positive (0)
›
Related tests:
FoundationOne® CDx (110)
FoundationOne® Liquid CDx (21)
Prosigna™ Breast Cancer Prognostic Gene Signature Assay (3)
FoundationOne® CDx (110)
FoundationOne® Liquid CDx (21)
Prosigna™ Breast Cancer Prognostic Gene Signature Assay (3)
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
sacituzumab govitecan-hziy
Sensitive: A1 - Approval
sacituzumab govitecan-hziy
Sensitive
:
A1
sacituzumab govitecan-hziy
Sensitive: A1 - Approval
sacituzumab govitecan-hziy
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
palbociclib
Sensitive: A1 - Approval
palbociclib
Sensitive
:
A1
palbociclib
Sensitive: A1 - Approval
palbociclib
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
ribociclib
Sensitive: A1 - Approval
ribociclib
Sensitive
:
A1
ribociclib
Sensitive: A1 - Approval
ribociclib
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
abemaciclib
Sensitive: A1 - Approval
abemaciclib
Sensitive
:
A1
abemaciclib
Sensitive: A1 - Approval
abemaciclib
Sensitive
:
A1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
ribociclib
Sensitive: A1 - Approval
ribociclib
Sensitive
:
A1
ribociclib
Sensitive: A1 - Approval
ribociclib
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
everolimus
Sensitive: A1 - Approval
everolimus
Sensitive
:
A1
everolimus
Sensitive: A1 - Approval
everolimus
Sensitive
:
A1
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
olaparib
Sensitive: A1 - Approval
olaparib
Sensitive
:
A1
olaparib
Sensitive: A1 - Approval
olaparib
Sensitive
:
A1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
letrozole
Sensitive: A1 - Approval
letrozole
Sensitive
:
A1
letrozole
Sensitive: A1 - Approval
letrozole
Sensitive
:
A1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
anastrozole
Sensitive: A1 - Approval
anastrozole
Sensitive
:
A1
anastrozole
Sensitive: A1 - Approval
anastrozole
Sensitive
:
A1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
talazoparib
Sensitive: A1 - Approval
talazoparib
Sensitive
:
A1
talazoparib
Sensitive: A1 - Approval
talazoparib
Sensitive
:
A1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
fulvestrant
Sensitive: A1 - Approval
fulvestrant
Sensitive
:
A1
fulvestrant
Sensitive: A1 - Approval
fulvestrant
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
fulvestrant
Sensitive: A1 - Approval
fulvestrant
Sensitive
:
A1
fulvestrant
Sensitive: A1 - Approval
fulvestrant
Sensitive
:
A1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
capivasertib
Sensitive: A1 - Approval
capivasertib
Sensitive
:
A1
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
lapatinib
Sensitive: A2 - Guideline
lapatinib
Sensitive
:
A2
lapatinib
Sensitive: A2 - Guideline
lapatinib
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
trastuzumab + pertuzumab
Sensitive: A2 - Guideline
trastuzumab + pertuzumab
Sensitive
:
A2
trastuzumab + pertuzumab
Sensitive: A2 - Guideline
trastuzumab + pertuzumab
Sensitive
:
A2
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
toremifene
Sensitive: A2 - Guideline
toremifene
Sensitive
:
A2
toremifene
Sensitive: A2 - Guideline
toremifene
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
HER2 inhibitor
Sensitive: A2 - Guideline
HER2 inhibitor
Sensitive
:
A2
HER2 inhibitor
Sensitive: A2 - Guideline
HER2 inhibitor
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
HER2 inhibitor + Aromatase inhibitor
Sensitive: A2 - Guideline
HER2 inhibitor + Aromatase inhibitor
Sensitive
:
A2
HER2 inhibitor + Aromatase inhibitor
Sensitive: A2 - Guideline
HER2 inhibitor + Aromatase inhibitor
Sensitive
:
A2
HR positive
Male Breast Cancer
HR positive
Male Breast Cancer
Aromatase inhibitor
Sensitive: A2 - Guideline
Aromatase inhibitor
Sensitive
:
A2
Aromatase inhibitor
Sensitive: A2 - Guideline
Aromatase inhibitor
Sensitive
:
A2
HR positive
Male Breast Cancer
HR positive
Male Breast Cancer
tamoxifen
Sensitive: A2 - Guideline
tamoxifen
Sensitive
:
A2
tamoxifen
Sensitive: A2 - Guideline
tamoxifen
Sensitive
:
A2
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
palbociclib
Resistant: A2 - Guideline
palbociclib
Resistant
:
A2
palbociclib
Resistant: A2 - Guideline
palbociclib
Resistant
:
A2
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
Aromatase inhibitor
Sensitive: A2 - Guideline
Aromatase inhibitor
Sensitive
:
A2
Aromatase inhibitor
Sensitive: A2 - Guideline
Aromatase inhibitor
Sensitive
:
A2
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
everolimus
Sensitive: A2 - Guideline
everolimus
Sensitive
:
A2
everolimus
Sensitive: A2 - Guideline
everolimus
Sensitive
:
A2
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
fulvestrant
Sensitive: A2 - Guideline
fulvestrant
Sensitive
:
A2
fulvestrant
Sensitive: A2 - Guideline
fulvestrant
Sensitive
:
A2
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
letrozole
Sensitive: A2 - Guideline
letrozole
Sensitive
:
A2
letrozole
Sensitive: A2 - Guideline
letrozole
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
trastuzumab + lapatinib
Sensitive: A2 - Guideline
trastuzumab + lapatinib
Sensitive
:
A2
trastuzumab + lapatinib
Sensitive: A2 - Guideline
trastuzumab + lapatinib
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
Aromatase inhibitor
Sensitive: A2 - Guideline
Aromatase inhibitor
Sensitive
:
A2
Aromatase inhibitor
Sensitive: A2 - Guideline
Aromatase inhibitor
Sensitive
:
A2
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
estradiol
Sensitive: A2 - Guideline
estradiol
Sensitive
:
A2
estradiol
Sensitive: A2 - Guideline
estradiol
Sensitive
:
A2
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
megestrol
Sensitive: A2 - Guideline
megestrol
Sensitive
:
A2
megestrol
Sensitive: A2 - Guideline
megestrol
Sensitive
:
A2
^
^
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