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BIOMARKER:
HER-2 positive
i
Other names:
ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification + RAS wild-type + BRAF wild-type (9)
HER-2 positive + HER-2 amplification (4)
RAS wild-type + HER-2 positive (4)
HER-2 amplification + KRAS G12D (3)
BRAF wild-type + HER-2 positive (2)
BRCA1 mutation + HER-2 negative (2)
BRCA2 mutation + HER-2 negative (2)
HER-2 S310F + HER-2 amplification (2)
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K (2)
HER-2 amplification + HER-2 L755S (2)
HER-2 amplification + PD-L1 expression (2)
HER-2 amplification + RAS wild-type (2)
HER-2 expression + HER-2 D769H (2)
HER-2 expression + HER-2 L869R (2)
HER-2 expression + HER-2 amplification (2)
HER-2 expression + TMB-H (2)
RAS wild-type + BRAF wild-type + HER-2 positive (2)
TMB-H + HER-2 positive (2)
AR positive + HER-2 amplification (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
EGFR L858R + HER-2 amplification + PIK3CA overexpression (1)
EGFR T790M + HER-2 amplification (1)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification (1)
ER negative + HER-2 positive + PGR positive + PIK3CA mutation (1)
ER positive + HER-2 D769H + HER-2 V777L (1)
ERBB2 G778A + CCNE1 amplification (1)
ERBB3 mutation + HER-2 amplification (1)
ERBB4 mutation + HER-2 positive (1)
HER-2 amplification + AXL expression (1)
HER-2 amplification + BRAF wild-type (1)
HER-2 amplification + CCNE1 expression (1)
HER-2 amplification + EGFR mutation (1)
HER-2 amplification + ER positive + PGR negative (1)
HER-2 amplification + HER-2 R157W (1)
HER-2 amplification + HER-2 mutation (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 elevation (1)
HER-2 elevation + TMB-H (1)
HER-2 elevation + TMB-L (1)
HER-2 exon 20 insertion + TMB-L + PD-L1 negative (1)
HER-2 mutation + HER-2 positive (1)
HER-2 mutation + TMB-H (1)
HER-2 overexpression + CCNE1 amplification (1)
HER-2 overexpression + HER-2 amplification (1)
HER-2 overexpression + KRAS G12C (1)
HER-2 overexpression + KRAS wild-type (1)
HER-2 overexpression + PTEN deletion (1)
HER-2 overexpression + RAS wild-type (1)
HER-2 positive + APC mutation (1)
HER-2 positive + GATA6 amplification (1)
HER-2 positive + MYC amplification (1)
HER-2 positive + TP53 mutation (1)
HER-2 underexpression + CCNE1 amplification (1)
HR positive + HER-2 amplification (1)
HR positive + HER-2 mutation (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS mutation + HER-2 positive (1)
MSI-H + HER-2 amplification (1)
MSI-H/dMMR + HER-2 mutation (1)
NF1 mutation + HER-2 positive (1)
PD-L1 overexpression + HER-2 exon 20 insertion (1)
PIK3C3 mutation + HER-2 positive (1)
PIK3CA H1047R + HER-2 amplification (1)
PIK3CA mutation + HER-2 amplification (1)
PIK3CA mutation + HER-2 positive (1)
PIK3CA mutation + HR positive + HER-2 negative (1)
PIK3R1 mutation + HER-2 positive (1)
POLE E790Q + ERBB2 amplification + TMB-H (1)
RAS wild-type + HER-2 amplification (1)
RAS wild-type + HER-2 overexpression (1)
STAT6 deletion + HER-2 overexpression (1)
ER negative + HER-2 positive + PIK3CA H1047R (0)
ER positive + HER-2 negative + ER mutation (0)
HER-2 amplification + KRAS G12C (0)
HER-2 exon 20 mutation + HER-2 amplification (0)
HER-2 positive + FGFR1 amplification (0)
HER-2-H (0)
HR positive + HER-2 negative + TMB-L (0)
PIK3CA E453K + HER-2 positive (0)
PIK3CA E542K + HER-2 positive (0)
PIK3CA E542Q + HER-2 positive (0)
PIK3CA H1047L + HER-2 positive (0)
PIK3CA H1047R + HER-2 positive (0)
PIK3CA N345K + HER-2 positive (0)
PIK3CA amplification + HER-2 positive (0)
HER-2 amplification + RAS wild-type + BRAF wild-type (9)
HER-2 positive + HER-2 amplification (4)
RAS wild-type + HER-2 positive (4)
HER-2 amplification + KRAS G12D (3)
BRAF wild-type + HER-2 positive (2)
BRCA1 mutation + HER-2 negative (2)
BRCA2 mutation + HER-2 negative (2)
HER-2 S310F + HER-2 amplification (2)
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K (2)
HER-2 amplification + HER-2 L755S (2)
HER-2 amplification + PD-L1 expression (2)
HER-2 amplification + RAS wild-type (2)
HER-2 expression + HER-2 D769H (2)
HER-2 expression + HER-2 L869R (2)
HER-2 expression + HER-2 amplification (2)
HER-2 expression + TMB-H (2)
RAS wild-type + BRAF wild-type + HER-2 positive (2)
TMB-H + HER-2 positive (2)
AR positive + HER-2 amplification (1)
BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
EGFR L858R + HER-2 amplification + PIK3CA overexpression (1)
EGFR T790M + HER-2 amplification (1)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification (1)
ER negative + HER-2 positive + PGR positive + PIK3CA mutation (1)
ER positive + HER-2 D769H + HER-2 V777L (1)
ERBB2 G778A + CCNE1 amplification (1)
ERBB3 mutation + HER-2 amplification (1)
ERBB4 mutation + HER-2 positive (1)
HER-2 amplification + AXL expression (1)
HER-2 amplification + BRAF wild-type (1)
HER-2 amplification + CCNE1 expression (1)
HER-2 amplification + EGFR mutation (1)
HER-2 amplification + ER positive + PGR negative (1)
HER-2 amplification + HER-2 R157W (1)
HER-2 amplification + HER-2 mutation (1)
HER-2 amplification + KRAS exon 2 wild-type (1)
HER-2 amplification + KRAS wild-type (1)
HER-2 elevation (1)
HER-2 elevation + TMB-H (1)
HER-2 elevation + TMB-L (1)
HER-2 exon 20 insertion + TMB-L + PD-L1 negative (1)
HER-2 mutation + HER-2 positive (1)
HER-2 mutation + TMB-H (1)
HER-2 overexpression + CCNE1 amplification (1)
HER-2 overexpression + HER-2 amplification (1)
HER-2 overexpression + KRAS G12C (1)
HER-2 overexpression + KRAS wild-type (1)
HER-2 overexpression + PTEN deletion (1)
HER-2 overexpression + RAS wild-type (1)
HER-2 positive + APC mutation (1)
HER-2 positive + GATA6 amplification (1)
HER-2 positive + MYC amplification (1)
HER-2 positive + TP53 mutation (1)
HER-2 underexpression + CCNE1 amplification (1)
HR positive + HER-2 amplification (1)
HR positive + HER-2 mutation (1)
KRAS G12D + HER-2 amplification + TMB-H (1)
KRAS mutation + HER-2 positive (1)
MSI-H + HER-2 amplification (1)
MSI-H/dMMR + HER-2 mutation (1)
NF1 mutation + HER-2 positive (1)
PD-L1 overexpression + HER-2 exon 20 insertion (1)
PIK3C3 mutation + HER-2 positive (1)
PIK3CA H1047R + HER-2 amplification (1)
PIK3CA mutation + HER-2 amplification (1)
PIK3CA mutation + HER-2 positive (1)
PIK3CA mutation + HR positive + HER-2 negative (1)
PIK3R1 mutation + HER-2 positive (1)
POLE E790Q + ERBB2 amplification + TMB-H (1)
RAS wild-type + HER-2 amplification (1)
RAS wild-type + HER-2 overexpression (1)
STAT6 deletion + HER-2 overexpression (1)
ER negative + HER-2 positive + PIK3CA H1047R (0)
ER positive + HER-2 negative + ER mutation (0)
HER-2 amplification + KRAS G12C (0)
HER-2 exon 20 mutation + HER-2 amplification (0)
HER-2 positive + FGFR1 amplification (0)
HER-2-H (0)
HR positive + HER-2 negative + TMB-L (0)
PIK3CA E453K + HER-2 positive (0)
PIK3CA E542K + HER-2 positive (0)
PIK3CA E542Q + HER-2 positive (0)
PIK3CA H1047L + HER-2 positive (0)
PIK3CA H1047R + HER-2 positive (0)
PIK3CA N345K + HER-2 positive (0)
PIK3CA amplification + HER-2 positive (0)
›
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
trastuzumab + tucatinib
Sensitive: A1 - Approval
trastuzumab + tucatinib
Sensitive
:
A1
trastuzumab + tucatinib
Sensitive: A1 - Approval
trastuzumab + tucatinib
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
trastuzumab + pertuzumab
Sensitive: A1 - Approval
trastuzumab + pertuzumab
Sensitive
:
A1
trastuzumab + pertuzumab
Sensitive: A1 - Approval
trastuzumab + pertuzumab
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
margetuximab-cmkb
Sensitive: A1 - Approval
margetuximab-cmkb
Sensitive
:
A1
margetuximab-cmkb
Sensitive: A1 - Approval
margetuximab-cmkb
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
trastuzumab
Sensitive: A1 - Approval
trastuzumab
Sensitive
:
A1
trastuzumab
Sensitive: A1 - Approval
trastuzumab
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
HER-2 positive
Gastric Cancer
HER-2 positive
Gastric Cancer
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
fam-trastuzumab deruxtecan-nxki
Sensitive: A1 - Approval
fam-trastuzumab deruxtecan-nxki
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: A1 - Approval
ado-trastuzumab emtansine
Sensitive
:
A1
ado-trastuzumab emtansine
Sensitive: A1 - Approval
ado-trastuzumab emtansine
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
trastuzumab
Sensitive: A1 - Approval
trastuzumab
Sensitive
:
A1
trastuzumab
Sensitive: A1 - Approval
trastuzumab
Sensitive
:
A1
HER-2 positive
Gastric Cancer
HER-2 positive
Gastric Cancer
pembrolizumab + trastuzumab
Sensitive: A1 - Approval
pembrolizumab + trastuzumab
Sensitive
:
A1
pembrolizumab + trastuzumab
Sensitive: A1 - Approval
pembrolizumab + trastuzumab
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
pertuzumab/trastuzumab/hyaluronidase-zzxf
Sensitive: A1 - Approval
pertuzumab / trastuzumab / hyaluronidase-zzxf
Sensitive
:
A1
pertuzumab/trastuzumab/hyaluronidase-zzxf
Sensitive: A1 - Approval
pertuzumab / trastuzumab / hyaluronidase-zzxf
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
trastuzumab-qyyp
Sensitive: A1 - Approval
trastuzumab-qyyp
Sensitive
:
A1
trastuzumab-qyyp
Sensitive: A1 - Approval
trastuzumab-qyyp
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
trastuzumab-dttb
Sensitive: A1 - Approval
trastuzumab-dttb
Sensitive
:
A1
trastuzumab-dttb
Sensitive: A1 - Approval
trastuzumab-dttb
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
trastuzumab-dkst
Sensitive: A1 - Approval
trastuzumab-dkst
Sensitive
:
A1
trastuzumab-dkst
Sensitive: A1 - Approval
trastuzumab-dkst
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
trastuzumab-anns
Sensitive: A1 - Approval
trastuzumab-anns
Sensitive
:
A1
trastuzumab-anns
Sensitive: A1 - Approval
trastuzumab-anns
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
trastuzumab-pkrb
Sensitive: A1 - Approval
trastuzumab-pkrb
Sensitive
:
A1
trastuzumab-pkrb
Sensitive: A1 - Approval
trastuzumab-pkrb
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 positive
Salivary Gland Cancer
HER-2 positive
Salivary Gland Cancer
trastuzumab
Sensitive: A1 - Approval
trastuzumab
Sensitive
:
A1
trastuzumab
Sensitive: A1 - Approval
trastuzumab
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
HER-2 positive
Gastric Cancer
HER-2 positive
Gastric Cancer
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
trastuzumab-strf
Sensitive: A1 - Approval
trastuzumab-strf
Sensitive
:
A1
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
HER-2 positive
Gastroesophageal Junction Adenocarcinoma
pembrolizumab + trastuzumab
Sensitive: A1 - Approval
pembrolizumab + trastuzumab
Sensitive
:
A1
pembrolizumab + trastuzumab
Sensitive: A1 - Approval
pembrolizumab + trastuzumab
Sensitive
:
A1
HER-2 positive
Colorectal Cancer
HER-2 positive
Colorectal Cancer
trastuzumab + pertuzumab
Sensitive: A1 - Approval
trastuzumab + pertuzumab
Sensitive
:
A1
trastuzumab + pertuzumab
Sensitive: A1 - Approval
trastuzumab + pertuzumab
Sensitive
:
A1
HER-2 positive
Colorectal Cancer
HER-2 positive
Colorectal Cancer
pertuzumab/trastuzumab/hyaluronidase-zzxf
Sensitive: A1 - Approval
pertuzumab / trastuzumab / hyaluronidase-zzxf
Sensitive
:
A1
pertuzumab/trastuzumab/hyaluronidase-zzxf
Sensitive: A1 - Approval
pertuzumab / trastuzumab / hyaluronidase-zzxf
Sensitive
:
A1
HER-2 positive
Gastric Cancer
HER-2 positive
Gastric Cancer
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
Sensitive: A2 - Guideline
Sensitive
:
A2
Sensitive: A2 - Guideline
Sensitive
:
A2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
Sensitive: A2 - Guideline
Sensitive
:
A2
Sensitive: A2 - Guideline
Sensitive
:
A2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
trastuzumab + abemaciclib
Sensitive: A2 - Guideline
trastuzumab + abemaciclib
Sensitive
:
A2
trastuzumab + abemaciclib
Sensitive: A2 - Guideline
trastuzumab + abemaciclib
Sensitive
:
A2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
Sensitive: A2 - Guideline
Sensitive
:
A2
Sensitive: A2 - Guideline
Sensitive
:
A2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
trastuzumab + lapatinib
Sensitive: A2 - Guideline
trastuzumab + lapatinib
Sensitive
:
A2
trastuzumab + lapatinib
Sensitive: A2 - Guideline
trastuzumab + lapatinib
Sensitive
:
A2
HER-2 positive
Gastroesophageal Cancer
HER-2 positive
Gastroesophageal Cancer
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
HER-2 positive
Esophageal Adenocarcinoma
HER-2 positive
Esophageal Adenocarcinoma
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
trastuzumab
Sensitive: A2 - Guideline
trastuzumab
Sensitive
:
A2
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