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DRUG:
Hepacid (pegargiminase)
i
Other names:
ADI-PEG 20, ADI-SSPEG 20, ADI-SS PEG, ADI-PEG-20, ADI-PEG20, ADI PEG20, ADI-SS PEG(20000), AD-PEG, ADI-PEG
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Associations
(3)
News
Trials
Company:
Polaris Pharma
Drug class:
Arginine depleter
‹
›
Associations
(3)
News
Trials
VERI cancer hierarchy
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ASS1 mutation
Malignant Pleural Mesothelioma
ASS1 mutation
Malignant Pleural Mesothelioma
cisplatin + pemetrexed + pegargiminase
Sensitive: C3 – Early Trials
cisplatin + pemetrexed + pegargiminase
Sensitive
:
C3
cisplatin + pemetrexed + pegargiminase
Sensitive: C3 – Early Trials
cisplatin + pemetrexed + pegargiminase
Sensitive
:
C3
ASS1 negative
Uveal Melanoma
ASS1 negative
Uveal Melanoma
cisplatin + pemetrexed + pegargiminase
Sensitive: C3 – Early Trials
cisplatin + pemetrexed + pegargiminase
Sensitive
:
C3
cisplatin + pemetrexed + pegargiminase
Sensitive: C3 – Early Trials
cisplatin + pemetrexed + pegargiminase
Sensitive
:
C3
ASS1 underexpression
Pancreatic Ductal Adenocarcinoma
ASS1 underexpression
Pancreatic Ductal Adenocarcinoma
panobinostat + pegargiminase
Sensitive: D – Preclinical
panobinostat + pegargiminase
Sensitive
:
D
panobinostat + pegargiminase
Sensitive: D – Preclinical
panobinostat + pegargiminase
Sensitive
:
D
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