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Association details:
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

A Phase 1 study of ADI-PEG20 (pegargiminase) combined with cisplatin and pemetrexed in ASS1-negative metastatic uveal melanoma

Published date:
04/25/2022
Excerpt:
Ten of fourteen ASS1-deficient patients with UM liver metastases and a median of one line of prior immunotherapy received ADIPemCis….Seven patients had stable disease with a median progression-free survival of 3.0 months (range, 1.3-8.1) and a median overall survival of 11.5 months (range, 3.2-36.9).
DOI:
10.1111/pcmr.13042