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BIOMARKER:
FGFR3 mutation
i
Other names:
FGFR3, ACH, CD333, CEK2, JTK4, Fibroblast growth factor receptor 3
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Entrez ID:
2261
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FGFR3 overexpression (11)
FGFR3 expression (2)
FGFR2 underexpression + FGFR3 overexpression (1)
FGFR3 positive (1)
FGFR2 underexpression + FGFR3 expression (0)
FGFR3 overexpression (11)
FGFR3 expression (2)
FGFR2 underexpression + FGFR3 overexpression (1)
FGFR3 positive (1)
FGFR2 underexpression + FGFR3 expression (0)
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Associations
News
Trials
VERI cancer hierarchy
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FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
erdafitinib
Sensitive: A1 - Approval
erdafitinib
Sensitive
:
A1
erdafitinib
Sensitive: A1 - Approval
erdafitinib
Sensitive
:
A1
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
BAY 1163877
Sensitive: B - Late Trials
BAY 1163877
Sensitive
:
B
BAY 1163877
Sensitive: B - Late Trials
BAY 1163877
Sensitive
:
B
FGFR3 mutation
Cholangiocarcinoma
FGFR3 mutation
Cholangiocarcinoma
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
FGFR3 mutation
Gastric Cancer
FGFR3 mutation
Gastric Cancer
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
FGFR3 mutation
Solid Tumor
FGFR3 mutation
Solid Tumor
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
FGFR3 mutation
Bladder Cancer
FGFR3 mutation
Bladder Cancer
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
erdafitinib
Sensitive: C1 - Off-label
erdafitinib
Sensitive
:
C1
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
infigratinib
Sensitive: C2 – Inclusion Criteria
infigratinib
Sensitive
:
C2
infigratinib
Sensitive: C2 – Inclusion Criteria
infigratinib
Sensitive
:
C2
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
pemigatinib
Sensitive: C2 – Inclusion Criteria
pemigatinib
Sensitive
:
C2
pemigatinib
Sensitive: C2 – Inclusion Criteria
pemigatinib
Sensitive
:
C2
FGFR3 mutation
Bladder Cancer
FGFR3 mutation
Bladder Cancer
infigratinib
Sensitive: C2 – Inclusion Criteria
infigratinib
Sensitive
:
C2
infigratinib
Sensitive: C2 – Inclusion Criteria
infigratinib
Sensitive
:
C2
FGFR3 mutation
Breast Cancer
FGFR3 mutation
Breast Cancer
infigratinib
Sensitive: C2 – Inclusion Criteria
infigratinib
Sensitive
:
C2
infigratinib
Sensitive: C2 – Inclusion Criteria
infigratinib
Sensitive
:
C2
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
futibatinib
Sensitive: C2 – Inclusion Criteria
futibatinib
Sensitive
:
C2
futibatinib
Sensitive: C2 – Inclusion Criteria
futibatinib
Sensitive
:
C2
FGFR3 mutation
Solid Tumor
FGFR3 mutation
Solid Tumor
futibatinib
Sensitive: C2 – Inclusion Criteria
futibatinib
Sensitive
:
C2
futibatinib
Sensitive: C2 – Inclusion Criteria
futibatinib
Sensitive
:
C2
FGFR3 mutation
Non Small Cell Lung Cancer
FGFR3 mutation
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
FGFR3 mutation
Non Small Cell Lung Cancer
FGFR3 mutation
Non Small Cell Lung Cancer
nintedanib
Sensitive: C3 – Early Trials
nintedanib
Sensitive
:
C3
nintedanib
Sensitive: C3 – Early Trials
nintedanib
Sensitive
:
C3
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
B-701
Sensitive: C3 – Early Trials
B-701
Sensitive
:
C3
B-701
Sensitive: C3 – Early Trials
B-701
Sensitive
:
C3
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
enfortumab vedotin-ejfv
Resistant: C3 – Early Trials
enfortumab vedotin-ejfv
Resistant
:
C3
enfortumab vedotin-ejfv
Resistant: C3 – Early Trials
enfortumab vedotin-ejfv
Resistant
:
C3
FGFR3 mutation
Melanoma
FGFR3 mutation
Melanoma
CTLA4 inhibitor
Sensitive: C3 – Early Trials
CTLA4 inhibitor
Sensitive
:
C3
CTLA4 inhibitor
Sensitive: C3 – Early Trials
CTLA4 inhibitor
Sensitive
:
C3
FGFR3 mutation
Melanoma
FGFR3 mutation
Melanoma
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
FGFR3 mutation
Melanoma
FGFR3 mutation
Melanoma
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
FGFR3 mutation
Solid Tumor
FGFR3 mutation
Solid Tumor
CPL304110
Sensitive: D – Preclinical
CPL304110
Sensitive
:
D
CPL304110
Sensitive: D – Preclinical
CPL304110
Sensitive
:
D
FGFR3 mutation
Endometrial Cancer
FGFR3 mutation
Endometrial Cancer
infigratinib
Sensitive: D – Preclinical
infigratinib
Sensitive
:
D
infigratinib
Sensitive: D – Preclinical
infigratinib
Sensitive
:
D
FGFR3 mutation
Urothelial Cancer
FGFR3 mutation
Urothelial Cancer
dasatinib + infigratinib
Sensitive: D – Preclinical
dasatinib + infigratinib
Sensitive
:
D
dasatinib + infigratinib
Sensitive: D – Preclinical
dasatinib + infigratinib
Sensitive
:
D
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