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BIOMARKER:

FGFR1 amplification

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Other names: FGFR1, BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM, Fibroblast growth factor receptor 1
Entrez ID:
FGFR1 amplification
Hormone Receptor Positive Breast Cancer
letrozole
Resistant: B - Late Trials
FGFR1 amplification
Lung Non-Small Cell Squamous Cancer
infigratinib
Sensitive: C2 – Inclusion Criteria
FGFR1 amplification
Breast Cancer
TAS 120
Sensitive: C2 – Inclusion Criteria
FGFR1 amplification
Gastric Cancer
ABSK-091
Sensitive: C2 – Inclusion Criteria
FGFR1 amplification
Bladder Cancer
infigratinib
Sensitive: C2 – Inclusion Criteria
FGFR1 amplification
Breast Cancer
infigratinib
Sensitive: C2 – Inclusion Criteria
FGFR1 amplification
Breast Cancer
TKI258
Sensitive: C2 – Inclusion Criteria
FGFR1 amplification
Breast Cancer
ABSK-091
Sensitive: C2 – Inclusion Criteria
FGFR1 amplification
Breast Cancer
Aromatase inhibitor
Resistant: C3 – Early Trials
FGFR1 amplification
HER2 Negative Breast Cancer
ABSK-091
Sensitive: C3 – Early Trials
FGFR1 amplification
Breast Cancer
Debio 1347
Resistant: C3 – Early Trials
FGFR1 amplification
Lung Non-Small Cell Squamous Cancer
TKI258
Sensitive: C3 – Early Trials
FGFR1 amplification
HER2 Negative Breast Cancer
pazopanib
Sensitive: C4 – Case Studies
FGFR1 amplification
NSCLC
M6123
Sensitive: D – Preclinical
FGFR1 amplification
Estrogen Receptor Positive Breast Cancer
ponatinib
Sensitive: D – Preclinical
FGFR1 amplification
Lung Cancer
TAS 120
Sensitive: D – Preclinical
FGFR1 amplification
CRC
eFT226
Sensitive: D – Preclinical
FGFR1 amplification
Small Cell Lung Cancer
TAS 120 + TAS-117
Sensitive: D – Preclinical
FGFR1 amplification
NSCLC
eFT226
Sensitive: D – Preclinical
FGFR1 amplification
Lung Cancer
ponatinib
Sensitive: D – Preclinical
FGFR1 amplification
Lung Non-Small Cell Squamous Cancer
ABSK-091
Sensitive: D – Preclinical
FGFR1 amplification
Breast Cancer
afimoxifene
Resistant: D – Preclinical
FGFR1 amplification
Breast Cancer
PD 0173074
Sensitive: D – Preclinical
FGFR1 amplification
Gastric Cancer
ponatinib
Sensitive: D – Preclinical
FGFR1 amplification
Breast Cancer
eFT226
Sensitive: D – Preclinical
FGFR1 amplification
Lung Cancer
ABSK-091 + BI 6727 + BI2536
Sensitive: D – Preclinical
FGFR1 amplification
Lung Cancer
BI 6727 + BI2536
Sensitive: D – Preclinical