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BIOMARKER:

ER Y537S

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Entrez ID:

Related biomarkers:

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ER amplification (1)

ER amplification (1)

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ER Y537S	HER2 Negative Breast Cancer	ER Y537S	HER2 Negative Breast Cancer	H3B-6545 Sensitive: C2 – Inclusion Criteria H3B-6545 Sensitive : C2	H3B-6545 Sensitive: C2 – Inclusion Criteria H3B-6545 Sensitive : C2
ER Y537S	HER2 Negative Breast Cancer	ER Y537S	HER2 Negative Breast Cancer	SAR439859 Sensitive: C3 – Early Trials SAR439859 Sensitive : C3	SAR439859 Sensitive: C3 – Early Trials SAR439859 Sensitive : C3
ER Y537S	Estrogen Receptor Positive Breast Cancer	ER Y537S	Estrogen Receptor Positive Breast Cancer	fulvestrant Sensitive: C3 – Early Trials fulvestrant Sensitive : C3	fulvestrant Sensitive: C3 – Early Trials fulvestrant Sensitive : C3
ER Y537S	HER2 Negative Breast Cancer	ER Y537S	HER2 Negative Breast Cancer	palbociclib + PF-05212384 Sensitive: C3 – Early Trials palbociclib + PF-05212384 Sensitive : C3	palbociclib + PF-05212384 Sensitive: C3 – Early Trials palbociclib + PF-05212384 Sensitive : C3
ER Y537S	Breast Cancer	ER Y537S	Breast Cancer	tamoxifen Sensitive: C4 – Case Studies tamoxifen Sensitive : C4	tamoxifen Sensitive: C4 – Case Studies tamoxifen Sensitive : C4
ER Y537S	Estrogen Receptor Positive Breast Cancer	ER Y537S	Estrogen Receptor Positive Breast Cancer	SAR439859 Sensitive: D – Preclinical SAR439859 Sensitive : D	SAR439859 Sensitive: D – Preclinical SAR439859 Sensitive : D
ER Y537S	Estrogen Receptor Positive Breast Cancer	ER Y537S	Estrogen Receptor Positive Breast Cancer	OP-1250 Sensitive: D – Preclinical OP-1250 Sensitive : D	OP-1250 Sensitive: D – Preclinical OP-1250 Sensitive : D
ER Y537S	Breast Cancer	ER Y537S	Breast Cancer	OP-1250 Sensitive: D – Preclinical OP-1250 Sensitive : D	OP-1250 Sensitive: D – Preclinical OP-1250 Sensitive : D
ER Y537S	Breast Cancer	ER Y537S	Breast Cancer	ZN-c5 Sensitive: D – Preclinical ZN-c5 Sensitive : D	ZN-c5 Sensitive: D – Preclinical ZN-c5 Sensitive : D
ER Y537S	Estrogen Receptor Positive Breast Cancer	ER Y537S	Estrogen Receptor Positive Breast Cancer	lasofoxifene Sensitive: D – Preclinical lasofoxifene Sensitive : D	lasofoxifene Sensitive: D – Preclinical lasofoxifene Sensitive : D
ER Y537S	Breast Cancer	ER Y537S	Breast Cancer	imlunestrant Sensitive: D – Preclinical imlunestrant Sensitive : D	imlunestrant Sensitive: D – Preclinical imlunestrant Sensitive : D
ER Y537S	Estrogen Receptor Positive Breast Cancer	ER Y537S	Estrogen Receptor Positive Breast Cancer	RG6171 Sensitive: D – Preclinical RG6171 Sensitive : D	RG6171 Sensitive: D – Preclinical RG6171 Sensitive : D