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BIOMARKER:
ER Y537S
i
Other names:
ESR1, Era, ESR, NR3A1, ER, ER beta
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Entrez ID:
2099
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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ER Y537S
HER2 Negative Breast Cancer
ER Y537S
HER2 Negative Breast Cancer
H3B-6545
Sensitive: C2 – Inclusion Criteria
H3B-6545
Sensitive
:
C2
H3B-6545
Sensitive: C2 – Inclusion Criteria
H3B-6545
Sensitive
:
C2
ER Y537S
HER2 Negative Breast Cancer
ER Y537S
HER2 Negative Breast Cancer
SAR439859
Sensitive: C3 – Early Trials
SAR439859
Sensitive
:
C3
SAR439859
Sensitive: C3 – Early Trials
SAR439859
Sensitive
:
C3
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
fulvestrant
Sensitive: C3 – Early Trials
fulvestrant
Sensitive
:
C3
fulvestrant
Sensitive: C3 – Early Trials
fulvestrant
Sensitive
:
C3
ER Y537S
HER2 Negative Breast Cancer
ER Y537S
HER2 Negative Breast Cancer
palbociclib + PF-05212384
Sensitive: C3 – Early Trials
palbociclib + PF-05212384
Sensitive
:
C3
palbociclib + PF-05212384
Sensitive: C3 – Early Trials
palbociclib + PF-05212384
Sensitive
:
C3
ER Y537S
Breast Cancer
ER Y537S
Breast Cancer
tamoxifen
Sensitive: C4 – Case Studies
tamoxifen
Sensitive
:
C4
tamoxifen
Sensitive: C4 – Case Studies
tamoxifen
Sensitive
:
C4
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
SAR439859
Sensitive: D – Preclinical
SAR439859
Sensitive
:
D
SAR439859
Sensitive: D – Preclinical
SAR439859
Sensitive
:
D
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
OP-1250
Sensitive: D – Preclinical
OP-1250
Sensitive
:
D
OP-1250
Sensitive: D – Preclinical
OP-1250
Sensitive
:
D
ER Y537S
Breast Cancer
ER Y537S
Breast Cancer
OP-1250
Sensitive: D – Preclinical
OP-1250
Sensitive
:
D
OP-1250
Sensitive: D – Preclinical
OP-1250
Sensitive
:
D
ER Y537S
Breast Cancer
ER Y537S
Breast Cancer
ZN-c5
Sensitive: D – Preclinical
ZN-c5
Sensitive
:
D
ZN-c5
Sensitive: D – Preclinical
ZN-c5
Sensitive
:
D
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
lasofoxifene
Sensitive: D – Preclinical
lasofoxifene
Sensitive
:
D
lasofoxifene
Sensitive: D – Preclinical
lasofoxifene
Sensitive
:
D
ER Y537S
Breast Cancer
ER Y537S
Breast Cancer
LY3484356
Sensitive: D – Preclinical
LY3484356
Sensitive
:
D
LY3484356
Sensitive: D – Preclinical
LY3484356
Sensitive
:
D
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
GDC-9545
Sensitive: D – Preclinical
GDC-9545
Sensitive
:
D
GDC-9545
Sensitive: D – Preclinical
GDC-9545
Sensitive
:
D
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
palbociclib + OP-1250
Sensitive: D – Preclinical
palbociclib + OP-1250
Sensitive
:
D
palbociclib + OP-1250
Sensitive: D – Preclinical
palbociclib + OP-1250
Sensitive
:
D
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
palbociclib
Sensitive: D – Preclinical
palbociclib
Sensitive
:
D
palbociclib
Sensitive: D – Preclinical
palbociclib
Sensitive
:
D
ER Y537S
Breast Cancer
ER Y537S
Breast Cancer
CB-103
Sensitive: D – Preclinical
CB-103
Sensitive
:
D
CB-103
Sensitive: D – Preclinical
CB-103
Sensitive
:
D
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
SCR-6852
Sensitive: D – Preclinical
SCR-6852
Sensitive
:
D
SCR-6852
Sensitive: D – Preclinical
SCR-6852
Sensitive
:
D
ER Y537S
Estrogen Receptor Positive Breast Cancer
ER Y537S
Estrogen Receptor Positive Breast Cancer
KPT-8602
Sensitive: D – Preclinical
KPT-8602
Sensitive
:
D
KPT-8602
Sensitive: D – Preclinical
KPT-8602
Sensitive
:
D
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