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BIOMARKER:
ER positive + MLH1 1835del3 + MSI-H/dMMR + TMB-H
i
Other names:
PGR, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, NR3C3, ESR1, Era, ESR, NR3A1, ER, ER beta, MLH1, COCA2, FCC2, HNPCC, HNPCC2, MutL homolog 1, MSI-H, Microsatellite instability - high, dMMR, TMB | Tumor Mutational Burden
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Entrez ID:
2099
;
5241
;
4292
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ER mutation (18)
ER Y537S (17)
ER D538G (11)
ESR1 mutation (9)
ER positive + ESR1 mutation (6)
MLH1 mutation (6)
ER Y537N (5)
MLH1 V384D (3)
PMS2 mutation + MLH1 mutation (3)
ER negative + PIK3CA H1047R (2)
PIK3CA mutation + ESR1 mutation (2)
ER D538G + ER F404L (1)
ER E380Q (1)
ER E380Q + ER F404L (1)
ER F404L (1)
ER L536Q (1)
ER T594T (1)
ER Y537C (1)
ER rs2234693 (1)
ESR1 rs1801132 (1)
ESR1 rs2228480 (1)
ESR1 rs2234693T>C (1)
ESR1 rs9322354 (1)
HR positive + PIK3CA H1047R (1)
HR positive + PIK3CA H1047R + ER D538G (1)
HR positive + PIK3CA H1047R + PIK3CA D350G + ER D538G (1)
PIK3CA H1047R + PIK3CA D959N + ER E380Q (1)
PIK3CA mutation + ER mutation (1)
MSI-H/dMMR + KMT2D mutation (1)
HER-2 negative + HR positive + ESR1 mutation + PIK3CA mutation (0)
ER mutation (18)
ER Y537S (17)
ER D538G (11)
ESR1 mutation (9)
ER positive + ESR1 mutation (6)
MLH1 mutation (6)
ER Y537N (5)
MLH1 V384D (3)
PMS2 mutation + MLH1 mutation (3)
ER negative + PIK3CA H1047R (2)
PIK3CA mutation + ESR1 mutation (2)
ER D538G + ER F404L (1)
ER E380Q (1)
ER E380Q + ER F404L (1)
ER F404L (1)
ER L536Q (1)
ER T594T (1)
ER Y537C (1)
ER rs2234693 (1)
ESR1 rs1801132 (1)
ESR1 rs2228480 (1)
ESR1 rs2234693T>C (1)
ESR1 rs9322354 (1)
HR positive + PIK3CA H1047R (1)
HR positive + PIK3CA H1047R + ER D538G (1)
HR positive + PIK3CA H1047R + PIK3CA D350G + ER D538G (1)
PIK3CA H1047R + PIK3CA D959N + ER E380Q (1)
PIK3CA mutation + ER mutation (1)
MSI-H/dMMR + KMT2D mutation (1)
HER-2 negative + HR positive + ESR1 mutation + PIK3CA mutation (0)
›
Associations
News
Trials
VERI cancer hierarchy
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ER positive + MLH1 1835del3 + MSI-H/dMMR + TMB-H
HER2 Negative Breast Cancer
ER positive + MLH1 1835del3 + MSI-H/dMMR + TMB-H
HER2 Negative Breast Cancer
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
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