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DRUG:

eltanexor (KPT-8602)

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News alerts, weekly reports and conference planners

Company:

Antengene, Karyopharm, Ono Pharma

Drug class:

XPO1 inhibitor, Nuclear export inhibitor

Related drugs:

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No biomarker	Myelodysplastic Syndrome	No biomarker	Myelodysplastic Syndrome	KPT-8602 Sensitive: B - Late Trials KPT-8602 Sensitive : B	KPT-8602 Sensitive: B - Late Trials KPT-8602 Sensitive : B
KRAS mutation	Colorectal Cancer	KRAS mutation	Colorectal Cancer	KPT-8602 Sensitive: C3 – Early Trials KPT-8602 Sensitive : C3	KPT-8602 Sensitive: C3 – Early Trials KPT-8602 Sensitive : C3
BCR-ABL1 fusion	Acute Lymphocytic Leukemia	BCR-ABL1 fusion	Acute Lymphocytic Leukemia	KPT-8602 Sensitive: D – Preclinical KPT-8602 Sensitive : D	KPT-8602 Sensitive: D – Preclinical KPT-8602 Sensitive : D
ER Y537S	Estrogen Receptor Positive Breast Cancer	ER Y537S	Estrogen Receptor Positive Breast Cancer	KPT-8602 Sensitive: D – Preclinical KPT-8602 Sensitive : D	KPT-8602 Sensitive: D – Preclinical KPT-8602 Sensitive : D
ER D538G	Estrogen Receptor Positive Breast Cancer	ER D538G	Estrogen Receptor Positive Breast Cancer	KPT-8602 Sensitive: D – Preclinical KPT-8602 Sensitive : D	KPT-8602 Sensitive: D – Preclinical KPT-8602 Sensitive : D