Pts with mCRC (≥50% KRAS mutant) in expansion cohorts received once daily oral ELTAfor 5 days per week at 20 (n = 7) or 30 (n = 23) mg….ELTA is well-tolerated with manageable AEs in mCRC. Even though this was small sample size, ELTA shows promise with a longer median PFS in this heavily treated population when compared to the currently available 3rdline therapies.