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BIOMARKER:

DKK1 overexpression

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Other names: DKK1, Dickkopf WNT Signaling Pathway Inhibitor 1, Dickkopf-Related Protein 1, SK, Dickkopf (Xenopus Laevis) Homolog 1, Dickkopf 1 Homolog (Xenopus Laevis), Dickkopf-Like Protein 1, Dickkopf 1 Homolog, Dickkopf-1 Like, Dickkopf-1, HDkk-1, DKK-1, Dkk-1
Entrez ID:
DKK1 overexpression
Gastroesophageal Junction Adenocarcinoma
DKN-01
Sensitive: B - Late Trials
DKK1 overexpression
Gastric Cancer
DKN-01
Sensitive: B - Late Trials
DKK1 overexpression
Gastroesophageal Junction Adenocarcinoma
pembrolizumab + DKN-01
Sensitive: C3 – Early Trials
DKK1 overexpression
Esophageal Squamous Cell Carcinoma
pembrolizumab + DKN-01
Sensitive: C3 – Early Trials
DKK1 overexpression
Esophageal Adenocarcinoma
pembrolizumab + DKN-01
Sensitive: C3 – Early Trials
DKK1 overexpression
Gastric Cancer
pembrolizumab + DKN-01
Sensitive: C3 – Early Trials
DKK1 overexpression
Endometrial Cancer
DKN-01
Sensitive: C3 – Early Trials
DKK1 overexpression
Esophageal Squamous Cell Carcinoma
DKN-01
Sensitive: C3 – Early Trials
DKK1 overexpression
Esophageal Adenocarcinoma
DKN-01
Sensitive: C3 – Early Trials
DKK1 overexpression
CRC
5-fluorouracil
Resistant: C3 – Early Trials
DKK1 overexpression
Gastroesophageal Junction Adenocarcinoma
tislelizumab + DKN-01
Sensitive: C3 – Early Trials