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BIOMARKER:

CTNNB1 mutation

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Entrez ID:

Related biomarkers:

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EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation (4)

GOPC-ROS1 fusion + CTNNB1 S45F (1)

AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)

EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation (4)

GOPC-ROS1 fusion + CTNNB1 S45F (1)

AKT1 E17K + CTNNB1 G34R + ER Y537S + MSI-H (0)

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CTNNB1 mutation	Colorectal Cancer	CTNNB1 mutation	Colorectal Cancer	panitumumab Sensitive: B - Late Trials panitumumab Sensitive : B	panitumumab Sensitive: B - Late Trials panitumumab Sensitive : B
CTNNB1 mutation	Endometrial Cancer	CTNNB1 mutation	Endometrial Cancer	PRI724 + SM04690 Sensitive: B - Late Trials PRI724 + SM04690 Sensitive : B	PRI724 + SM04690 Sensitive: B - Late Trials PRI724 + SM04690 Sensitive : B
CTNNB1 mutation	Endometrial Cancer	CTNNB1 mutation	Endometrial Cancer	SM04690 Sensitive: B - Late Trials SM04690 Sensitive : B	SM04690 Sensitive: B - Late Trials SM04690 Sensitive : B
CTNNB1 mutation	Endometrial Cancer	CTNNB1 mutation	Endometrial Cancer	everolimus + letrozole Sensitive: C3 – Early Trials everolimus + letrozole Sensitive : C3	everolimus + letrozole Sensitive: C3 – Early Trials everolimus + letrozole Sensitive : C3
CTNNB1 mutation	Endometrial Cancer	CTNNB1 mutation	Endometrial Cancer	temsirolimus Sensitive: C3 – Early Trials temsirolimus Sensitive : C3	temsirolimus Sensitive: C3 – Early Trials temsirolimus Sensitive : C3
CTNNB1 mutation	Non Small Cell Lung Cancer	CTNNB1 mutation	Non Small Cell Lung Cancer	cabozantinib capsule Sensitive: C3 – Early Trials cabozantinib capsule Sensitive : C3	cabozantinib capsule Sensitive: C3 – Early Trials cabozantinib capsule Sensitive : C3
CTNNB1 mutation	Hepatocellular Cancer	CTNNB1 mutation	Hepatocellular Cancer	Immunotherapy Sensitive: C3 – Early Trials Immunotherapy Sensitive : C3	Immunotherapy Sensitive: C3 – Early Trials Immunotherapy Sensitive : C3
CTNNB1 mutation	Hepatocellular Cancer	CTNNB1 mutation	Hepatocellular Cancer	nivolumab Sensitive: C3 – Early Trials nivolumab Sensitive : C3	nivolumab Sensitive: C3 – Early Trials nivolumab Sensitive : C3
CTNNB1 mutation	Lung Cancer	CTNNB1 mutation	Lung Cancer	VIC-1911 Sensitive: D – Preclinical VIC-1911 Sensitive : D	VIC-1911 Sensitive: D – Preclinical VIC-1911 Sensitive : D