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BIOMARKER:
CLDN18.2 expression
i
Other names:
CLDN18, Claudin-18, Surfactant, Pulmonary Associated Protein J, Surfactant Associated 5, SFTA5, SFTPJ
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Entrez ID:
51208
Related biomarkers:
Expression
Fusion
‹
CLDN18.2 positive (15)
CLDN18.2 overexpression (6)
CLDN18.2 expression + HER-2 negative (2)
CLDN18.2 positive + HER-2 negative (2)
CLDN18.2 underexpression (2)
HER-2 negative + CLDN18.2 positive (0)
CLDN18.2 positive (15)
CLDN18.2 overexpression (6)
CLDN18.2 expression + HER-2 negative (2)
CLDN18.2 positive + HER-2 negative (2)
CLDN18.2 underexpression (2)
HER-2 negative + CLDN18.2 positive (0)
›
Related tests:
VENTANA CLDN18 (43-14A) Assay (2)
VENTANA CLDN18 (43-14A) Assay (2)
Associations
News
Trials
VERI cancer hierarchy
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CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
EO-3021
Sensitive: B - Late Trials
EO-3021
Sensitive
:
B
EO-3021
Sensitive: B - Late Trials
EO-3021
Sensitive
:
B
CLDN18.2 expression
Gastroesophageal Junction Adenocarcinoma
CLDN18.2 expression
Gastroesophageal Junction Adenocarcinoma
EO-3021
Sensitive: B - Late Trials
EO-3021
Sensitive
:
B
EO-3021
Sensitive: B - Late Trials
EO-3021
Sensitive
:
B
CLDN18.2 expression
Esophageal Adenocarcinoma
CLDN18.2 expression
Esophageal Adenocarcinoma
zolbetuximab-clzb
Sensitive: C2 – Inclusion Criteria
zolbetuximab-clzb
Sensitive
:
C2
zolbetuximab-clzb
Sensitive: C2 – Inclusion Criteria
zolbetuximab-clzb
Sensitive
:
C2
CLDN18.2 expression
Gastroesophageal Junction Adenocarcinoma
CLDN18.2 expression
Gastroesophageal Junction Adenocarcinoma
zolbetuximab-clzb
Sensitive: C2 – Inclusion Criteria
zolbetuximab-clzb
Sensitive
:
C2
zolbetuximab-clzb
Sensitive: C2 – Inclusion Criteria
zolbetuximab-clzb
Sensitive
:
C2
CLDN18.2 expression
Gastric Adenocarcinoma
CLDN18.2 expression
Gastric Adenocarcinoma
zolbetuximab-clzb
Sensitive: C2 – Inclusion Criteria
zolbetuximab-clzb
Sensitive
:
C2
zolbetuximab-clzb
Sensitive: C2 – Inclusion Criteria
zolbetuximab-clzb
Sensitive
:
C2
CLDN18.2 expression
Pancreatic Cancer
CLDN18.2 expression
Pancreatic Cancer
SOT102
Sensitive: C2 – Inclusion Criteria
SOT102
Sensitive
:
C2
SOT102
Sensitive: C2 – Inclusion Criteria
SOT102
Sensitive
:
C2
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
SOT102
Sensitive: C2 – Inclusion Criteria
SOT102
Sensitive
:
C2
SOT102
Sensitive: C2 – Inclusion Criteria
SOT102
Sensitive
:
C2
CLDN18.2 expression
Pancreatic Cancer
CLDN18.2 expression
Pancreatic Cancer
ASP2138
Sensitive: C2 – Inclusion Criteria
ASP2138
Sensitive
:
C2
ASP2138
Sensitive: C2 – Inclusion Criteria
ASP2138
Sensitive
:
C2
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
ASP2138
Sensitive: C2 – Inclusion Criteria
ASP2138
Sensitive
:
C2
ASP2138
Sensitive: C2 – Inclusion Criteria
ASP2138
Sensitive
:
C2
CLDN18.2 expression
Pancreatic Cancer
CLDN18.2 expression
Pancreatic Cancer
EO-3021
Sensitive: C2 – Inclusion Criteria
EO-3021
Sensitive
:
C2
EO-3021
Sensitive: C2 – Inclusion Criteria
EO-3021
Sensitive
:
C2
CLDN18.2 expression
Solid Tumor
CLDN18.2 expression
Solid Tumor
EO-3021
Sensitive: C2 – Inclusion Criteria
EO-3021
Sensitive
:
C2
EO-3021
Sensitive: C2 – Inclusion Criteria
EO-3021
Sensitive
:
C2
CLDN18.2 expression
Lung Cancer
CLDN18.2 expression
Lung Cancer
EO-3021
Sensitive: C2 – Inclusion Criteria
EO-3021
Sensitive
:
C2
EO-3021
Sensitive: C2 – Inclusion Criteria
EO-3021
Sensitive
:
C2
CLDN18.2 expression
Esophageal Cancer
CLDN18.2 expression
Esophageal Cancer
AZD5863
Sensitive: C2 – Inclusion Criteria
AZD5863
Sensitive
:
C2
AZD5863
Sensitive: C2 – Inclusion Criteria
AZD5863
Sensitive
:
C2
CLDN18.2 expression
Pancreatic Cancer
CLDN18.2 expression
Pancreatic Cancer
AZD5863
Sensitive: C2 – Inclusion Criteria
AZD5863
Sensitive
:
C2
AZD5863
Sensitive: C2 – Inclusion Criteria
AZD5863
Sensitive
:
C2
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
AZD5863
Sensitive: C2 – Inclusion Criteria
AZD5863
Sensitive
:
C2
AZD5863
Sensitive: C2 – Inclusion Criteria
AZD5863
Sensitive
:
C2
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
Q-1802
Sensitive: C3 – Early Trials
Q-1802
Sensitive
:
C3
Q-1802
Sensitive: C3 – Early Trials
Q-1802
Sensitive
:
C3
CLDN18.2 expression
Gastroesophageal Cancer
CLDN18.2 expression
Gastroesophageal Cancer
TJ-CD4B
Sensitive: C3 – Early Trials
TJ-CD4B
Sensitive
:
C3
TJ-CD4B
Sensitive: C3 – Early Trials
TJ-CD4B
Sensitive
:
C3
CLDN18.2 expression
Pancreatic Cancer
CLDN18.2 expression
Pancreatic Cancer
CT041
Sensitive: C4 – Case Studies
CT041
Sensitive
:
C4
CT041
Sensitive: C4 – Case Studies
CT041
Sensitive
:
C4
CLDN18.2 expression
Pancreatic Cancer
CLDN18.2 expression
Pancreatic Cancer
IBI-345
Sensitive: C4 – Case Studies
IBI-345
Sensitive
:
C4
IBI-345
Sensitive: C4 – Case Studies
IBI-345
Sensitive
:
C4
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
IBI-345
Sensitive: C4 – Case Studies
IBI-345
Sensitive
:
C4
IBI-345
Sensitive: C4 – Case Studies
IBI-345
Sensitive
:
C4
CLDN18.2 expression
Gastroesophageal Junction Adenocarcinoma
CLDN18.2 expression
Gastroesophageal Junction Adenocarcinoma
IBI-345
Sensitive: C4 – Case Studies
IBI-345
Sensitive
:
C4
IBI-345
Sensitive: C4 – Case Studies
IBI-345
Sensitive
:
C4
CLDN18.2 expression
Pancreatic Cancer
CLDN18.2 expression
Pancreatic Cancer
ZL-1211
Sensitive: D – Preclinical
ZL-1211
Sensitive
:
D
ZL-1211
Sensitive: D – Preclinical
ZL-1211
Sensitive
:
D
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
ZL-1211
Sensitive: D – Preclinical
ZL-1211
Sensitive
:
D
ZL-1211
Sensitive: D – Preclinical
ZL-1211
Sensitive
:
D
CLDN18.2 expression
Solid Tumor
CLDN18.2 expression
Solid Tumor
TJ-CD4B
Sensitive: D – Preclinical
TJ-CD4B
Sensitive
:
D
TJ-CD4B
Sensitive: D – Preclinical
TJ-CD4B
Sensitive
:
D
CLDN18.2 expression
Lung Adenocarcinoma
CLDN18.2 expression
Lung Adenocarcinoma
SOT102
Sensitive: D – Preclinical
SOT102
Sensitive
:
D
SOT102
Sensitive: D – Preclinical
SOT102
Sensitive
:
D
CLDN18.2 expression
Colon Cancer
CLDN18.2 expression
Colon Cancer
SOT102
Sensitive: D – Preclinical
SOT102
Sensitive
:
D
SOT102
Sensitive: D – Preclinical
SOT102
Sensitive
:
D
CLDN18.2 expression
Hepatocellular Cancer
CLDN18.2 expression
Hepatocellular Cancer
SOT102
Sensitive: D – Preclinical
SOT102
Sensitive
:
D
SOT102
Sensitive: D – Preclinical
SOT102
Sensitive
:
D
CLDN18.2 expression
Endometrial Cancer
CLDN18.2 expression
Endometrial Cancer
CLDN18.2-targeted antibody-drug conjugate
Sensitive: D – Preclinical
CLDN18.2-targeted antibody-drug conjugate
Sensitive
:
D
CLDN18.2-targeted antibody-drug conjugate
Sensitive: D – Preclinical
CLDN18.2-targeted antibody-drug conjugate
Sensitive
:
D
CLDN18.2 expression
Ovarian Cancer
CLDN18.2 expression
Ovarian Cancer
CLDN18.2-targeted antibody-drug conjugate
Sensitive: D – Preclinical
CLDN18.2-targeted antibody-drug conjugate
Sensitive
:
D
CLDN18.2-targeted antibody-drug conjugate
Sensitive: D – Preclinical
CLDN18.2-targeted antibody-drug conjugate
Sensitive
:
D
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
TJ-CD4B
Sensitive: D – Preclinical
TJ-CD4B
Sensitive
:
D
TJ-CD4B
Sensitive: D – Preclinical
TJ-CD4B
Sensitive
:
D
CLDN18.2 expression
Gastric Cancer
CLDN18.2 expression
Gastric Cancer
nivolumab + TJ-CD4B
Sensitive: D – Preclinical
nivolumab + TJ-CD4B
Sensitive
:
D
nivolumab + TJ-CD4B
Sensitive: D – Preclinical
nivolumab + TJ-CD4B
Sensitive
:
D
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