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BIOMARKER:
Chr t(4;14)
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Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
Sensitive: B - Late Trials
Sensitive
:
B
Sensitive: B - Late Trials
Sensitive
:
B
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
daratumumab
Sensitive: B - Late Trials
daratumumab
Sensitive
:
B
daratumumab
Sensitive: B - Late Trials
daratumumab
Sensitive
:
B
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
lenalidomide + isatuximab-irfc
Sensitive: B - Late Trials
lenalidomide + isatuximab-irfc
Sensitive
:
B
lenalidomide + isatuximab-irfc
Sensitive: B - Late Trials
lenalidomide + isatuximab-irfc
Sensitive
:
B
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
Sensitive: C2 – Inclusion Criteria
Sensitive
:
C2
Sensitive: C2 – Inclusion Criteria
Sensitive
:
C2
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
lenalidomide + ixazomib
Sensitive: C3 – Early Trials
lenalidomide + ixazomib
Sensitive
:
C3
lenalidomide + ixazomib
Sensitive: C3 – Early Trials
lenalidomide + ixazomib
Sensitive
:
C3
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
Proteasome inhibitor + Immunomodulator
Sensitive: C3 – Early Trials
Proteasome inhibitor + Immunomodulator
Sensitive
:
C3
Proteasome inhibitor + Immunomodulator
Sensitive: C3 – Early Trials
Proteasome inhibitor + Immunomodulator
Sensitive
:
C3
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
bortezomib
Resistant: C3 – Early Trials
bortezomib
Resistant
:
C3
bortezomib
Resistant: C3 – Early Trials
bortezomib
Resistant
:
C3
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
lenalidomide + elotuzumab
Sensitive: C3 – Early Trials
lenalidomide + elotuzumab
Sensitive
:
C3
lenalidomide + elotuzumab
Sensitive: C3 – Early Trials
lenalidomide + elotuzumab
Sensitive
:
C3
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
lenalidomide
Sensitive: C3 – Early Trials
lenalidomide
Sensitive
:
C3
lenalidomide
Sensitive: C3 – Early Trials
lenalidomide
Sensitive
:
C3
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
elranatamab-bcmm
Sensitive: C3 – Early Trials
elranatamab-bcmm
Sensitive
:
C3
elranatamab-bcmm
Sensitive: C3 – Early Trials
elranatamab-bcmm
Sensitive
:
C3
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
midostaurin
Sensitive: D – Preclinical
midostaurin
Sensitive
:
D
midostaurin
Sensitive: D – Preclinical
midostaurin
Sensitive
:
D
Chr t(4;14)
Multiple Myeloma
Chr t(4;14)
Multiple Myeloma
PFI-3
Sensitive: D – Preclinical
PFI-3
Sensitive
:
D
PFI-3
Sensitive: D – Preclinical
PFI-3
Sensitive
:
D
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