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BIOMARKER:
Chr t(11;14) + BCL2 overexpression
i
Other names:
BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2
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Entrez ID:
596
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
MYC rearrangement + BCL2 rearrangement (22)
BCL2 mutation (6)
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement (6)
BCL2 G101V (4)
BCL2 rearrangement (3)
MYC translocation + BCL2 translocation (3)
BCL2 D103Y (2)
BCL2 F104I (1)
BCL2 G101V + SF3B1 mutation (1)
BCL2 N103E (1)
BCL2 N103Y (1)
BCL2 N107_N110dup (1)
BCL2 V156N (1)
EZH2 mutation + BCL2 translocation (1)
MYC translocation + BCL6 translocation + BCL2 translocation (1)
TP53 mutation + BCL2 rearrangement (1)
BCL2 translocation (0)
MYC rearrangement + BCL2 rearrangement+ BCL6 rearrangement (0)
MYC rearrangement + BCL2 rearrangement (22)
BCL2 mutation (6)
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement (6)
BCL2 G101V (4)
BCL2 rearrangement (3)
MYC translocation + BCL2 translocation (3)
BCL2 D103Y (2)
BCL2 F104I (1)
BCL2 G101V + SF3B1 mutation (1)
BCL2 N103E (1)
BCL2 N103Y (1)
BCL2 N107_N110dup (1)
BCL2 V156N (1)
EZH2 mutation + BCL2 translocation (1)
MYC translocation + BCL6 translocation + BCL2 translocation (1)
TP53 mutation + BCL2 rearrangement (1)
BCL2 translocation (0)
MYC rearrangement + BCL2 rearrangement+ BCL6 rearrangement (0)
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Trials
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Chr t(11;14) + BCL2 overexpression
Multiple Myeloma
Chr t(11;14) + BCL2 overexpression
Multiple Myeloma
venetoclax + daratumumab
Sensitive: D – Preclinical
venetoclax + daratumumab
Sensitive
:
D
venetoclax + daratumumab
Sensitive: D – Preclinical
venetoclax + daratumumab
Sensitive
:
D
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