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DRUG CLASS:

CD123-targeted antibody-drug conjugate

DRUG CLASS:

CD123-targeted antibody-drug conjugate

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CD123 positive	Acute Myelogenous Leukemia	CD123 positive	Acute Myelogenous Leukemia	IMGN632 Sensitive: C2 – Inclusion Criteria IMGN632 Sensitive : C2	IMGN632 Sensitive: C2 – Inclusion Criteria IMGN632 Sensitive : C2
CD123 positive	Acute Myelogenous Leukemia	CD123 positive	Acute Myelogenous Leukemia	venetoclax + IMGN632 Sensitive: C2 – Inclusion Criteria venetoclax + IMGN632 Sensitive : C2	venetoclax + IMGN632 Sensitive: C2 – Inclusion Criteria venetoclax + IMGN632 Sensitive : C2
IL3RA positive	Acute Myelogenous Leukemia	IL3RA positive	Acute Myelogenous Leukemia	IMGN632 Sensitive: C2 – Inclusion Criteria IMGN632 Sensitive : C2	IMGN632 Sensitive: C2 – Inclusion Criteria IMGN632 Sensitive : C2
CD123 positive	Hodgkin Lymphoma	CD123 positive	Hodgkin Lymphoma	VIP943 Sensitive: D – Preclinical VIP943 Sensitive : D	VIP943 Sensitive: D – Preclinical VIP943 Sensitive : D
CD123 positive	Acute Myelogenous Leukemia	CD123 positive	Acute Myelogenous Leukemia	VIP943 Sensitive: D – Preclinical VIP943 Sensitive : D	VIP943 Sensitive: D – Preclinical VIP943 Sensitive : D
CD123 positive	Acute Myelogenous Leukemia	CD123 positive	Acute Myelogenous Leukemia	SGN-CD123A Sensitive: D – Preclinical SGN-CD123A Sensitive : D	SGN-CD123A Sensitive: D – Preclinical SGN-CD123A Sensitive : D
FLT3 mutation	Acute Myelogenous Leukemia	FLT3 mutation	Acute Myelogenous Leukemia	quizartinib + SGN-CD123A Sensitive: D – Preclinical quizartinib + SGN-CD123A Sensitive : D	quizartinib + SGN-CD123A Sensitive: D – Preclinical quizartinib + SGN-CD123A Sensitive : D
IL3RA expression	Childhood B Acute Lymphoblastic Leukemia	IL3RA expression	Childhood B Acute Lymphoblastic Leukemia	IMGN632 Sensitive: D – Preclinical IMGN632 Sensitive : D	IMGN632 Sensitive: D – Preclinical IMGN632 Sensitive : D
CD123 positive	Acute Myelogenous Leukemia	CD123 positive	Acute Myelogenous Leukemia	BYON4413 Sensitive: D – Preclinical BYON4413 Sensitive : D	BYON4413 Sensitive: D – Preclinical BYON4413 Sensitive : D