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BIOMARKER:
CBL mutation
i
Other names:
CBL, c-Cbl, CBL2, RNF55, Cbl proto-oncogene, E3 ubiquitin protein ligase
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Entrez ID:
867
Related biomarkers:
Mutation
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CBL mutation
Myelodysplastic Syndrome
CBL mutation
Myelodysplastic Syndrome
ruxolitinib
Sensitive: A2 - Guideline
ruxolitinib
Sensitive
:
A2
ruxolitinib
Sensitive: A2 - Guideline
ruxolitinib
Sensitive
:
A2
CBL mutation
Acute Myelogenous Leukemia
CBL mutation
Acute Myelogenous Leukemia
gilteritinib
Resistant: B - Late Trials
gilteritinib
Resistant
:
B
gilteritinib
Resistant: B - Late Trials
gilteritinib
Resistant
:
B
CBL mutation
Myelodysplastic Syndrome
CBL mutation
Myelodysplastic Syndrome
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
CBL mutation
Chronic Myelomonocytic Leukemia
CBL mutation
Chronic Myelomonocytic Leukemia
lenzilumab
Sensitive: C2 – Inclusion Criteria
lenzilumab
Sensitive
:
C2
lenzilumab
Sensitive: C2 – Inclusion Criteria
lenzilumab
Sensitive
:
C2
CBL mutation
Acute Myelogenous Leukemia
CBL mutation
Acute Myelogenous Leukemia
cytarabine/daunorubicin liposomal formulation
Resistant: C3 – Early Trials
cytarabine / daunorubicin liposomal formulation
Resistant
:
C3
cytarabine/daunorubicin liposomal formulation
Resistant: C3 – Early Trials
cytarabine / daunorubicin liposomal formulation
Resistant
:
C3
CBL mutation
Sarcoma
CBL mutation
Sarcoma
MGCD516
Sensitive: C3 – Early Trials
MGCD516
Sensitive
:
C3
MGCD516
Sensitive: C3 – Early Trials
MGCD516
Sensitive
:
C3
CBL mutation
Non Small Cell Lung Cancer
CBL mutation
Non Small Cell Lung Cancer
MGCD516
Sensitive: C3 – Early Trials
MGCD516
Sensitive
:
C3
MGCD516
Sensitive: C3 – Early Trials
MGCD516
Sensitive
:
C3
CBL mutation
Melanoma
CBL mutation
Melanoma
MGCD516
Sensitive: C3 – Early Trials
MGCD516
Sensitive
:
C3
MGCD516
Sensitive: C3 – Early Trials
MGCD516
Sensitive
:
C3
CBL mutation
Non Small Cell Lung Cancer
CBL mutation
Non Small Cell Lung Cancer
SU11274
Sensitive: D – Preclinical
SU11274
Sensitive
:
D
SU11274
Sensitive: D – Preclinical
SU11274
Sensitive
:
D
CBL mutation
Chronic Myelomonocytic Leukemia
CBL mutation
Chronic Myelomonocytic Leukemia
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
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