BRAF V600

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Entrez ID:

673

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FoundationOne® CDx (110)

BRAF V600	Melanoma	BRAF V600	Melanoma	atezolizumab + vemurafenib + cobimetinib Sensitive: A1 - Approval atezolizumab + vemurafenib + cobimetinib Sensitive : A1	atezolizumab + vemurafenib + cobimetinib Sensitive: A1 - Approval atezolizumab + vemurafenib + cobimetinib Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	binimetinib + encorafenib Sensitive: A1 - Approval binimetinib + encorafenib Sensitive : A1	binimetinib + encorafenib Sensitive: A1 - Approval binimetinib + encorafenib Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	vemurafenib + cobimetinib Sensitive: A1 - Approval vemurafenib + cobimetinib Sensitive : A1	vemurafenib + cobimetinib Sensitive: A1 - Approval vemurafenib + cobimetinib Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	dabrafenib Sensitive: A1 - Approval dabrafenib Sensitive : A1	dabrafenib Sensitive: A1 - Approval dabrafenib Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	trametinib + dabrafenib Sensitive: A1 - Approval trametinib + dabrafenib Sensitive : A1	trametinib + dabrafenib Sensitive: A1 - Approval trametinib + dabrafenib Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	trametinib Sensitive: A1 - Approval trametinib Sensitive : A1	trametinib Sensitive: A1 - Approval trametinib Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	vemurafenib Sensitive: A1 - Approval vemurafenib Sensitive : A1	vemurafenib Sensitive: A1 - Approval vemurafenib Sensitive : A1
BRAF V600	Non Small Cell Lung Cancer	BRAF V600	Non Small Cell Lung Cancer	trametinib + dabrafenib Sensitive: A1 - Approval trametinib + dabrafenib Sensitive : A1	trametinib + dabrafenib Sensitive: A1 - Approval trametinib + dabrafenib Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	nivolumab Sensitive: A1 - Approval nivolumab Sensitive : A1	nivolumab Sensitive: A1 - Approval nivolumab Sensitive : A1
BRAF V600	Melanoma	BRAF V600	Melanoma	pembrolizumab Sensitive: A1 - Approval pembrolizumab Sensitive : A1	pembrolizumab Sensitive: A1 - Approval pembrolizumab Sensitive : A1
BRAF V600	Glioma	BRAF V600	Glioma	tovorafenib Sensitive: A1 - Approval tovorafenib Sensitive : A1	tovorafenib Sensitive: A1 - Approval tovorafenib Sensitive : A1
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	trametinib Resistant: A2 - Guideline trametinib Resistant : A2	trametinib Resistant: A2 - Guideline trametinib Resistant : A2
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	atezolizumab + vemurafenib + cobimetinib Sensitive: A2 - Guideline atezolizumab + vemurafenib + cobimetinib Sensitive : A2	atezolizumab + vemurafenib + cobimetinib Sensitive: A2 - Guideline atezolizumab + vemurafenib + cobimetinib Sensitive : A2
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	vemurafenib + cobimetinib Sensitive: A2 - Guideline vemurafenib + cobimetinib Sensitive : A2	vemurafenib + cobimetinib Sensitive: A2 - Guideline vemurafenib + cobimetinib Sensitive : A2
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	binimetinib + encorafenib Sensitive: A2 - Guideline binimetinib + encorafenib Sensitive : A2	binimetinib + encorafenib Sensitive: A2 - Guideline binimetinib + encorafenib Sensitive : A2
BRAF V600	Melanoma	BRAF V600	Melanoma	BRAF inhibitor + MEK inhibitor Sensitive: A2 - Guideline BRAF inhibitor + MEK inhibitor Sensitive : A2	BRAF inhibitor + MEK inhibitor Sensitive: A2 - Guideline BRAF inhibitor + MEK inhibitor Sensitive : A2
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	trametinib + dabrafenib Sensitive: A2 - Guideline trametinib + dabrafenib Sensitive : A2	trametinib + dabrafenib Sensitive: A2 - Guideline trametinib + dabrafenib Sensitive : A2
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	nivolumab + ipilimumab Sensitive: A2 - Guideline nivolumab + ipilimumab Sensitive : A2	nivolumab + ipilimumab Sensitive: A2 - Guideline nivolumab + ipilimumab Sensitive : A2
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	pembrolizumab + dabrafenib Sensitive: A2 - Guideline pembrolizumab + dabrafenib Sensitive : A2	pembrolizumab + dabrafenib Sensitive: A2 - Guideline pembrolizumab + dabrafenib Sensitive : A2
BRAF V600	Cutaneous Melanoma	BRAF V600	Cutaneous Melanoma	pembrolizumab + trametinib Sensitive: A2 - Guideline pembrolizumab + trametinib Sensitive : A2	pembrolizumab + trametinib Sensitive: A2 - Guideline pembrolizumab + trametinib Sensitive : A2
BRAF V600	Rectal Cancer	BRAF V600	Rectal Cancer	cetuximab + encorafenib Sensitive: A2 - Guideline cetuximab + encorafenib Sensitive : A2	cetuximab + encorafenib Sensitive: A2 - Guideline cetuximab + encorafenib Sensitive : A2
BRAF V600	Rectal Cancer	BRAF V600	Rectal Cancer	panitumumab + encorafenib Sensitive: A2 - Guideline panitumumab + encorafenib Sensitive : A2	panitumumab + encorafenib Sensitive: A2 - Guideline panitumumab + encorafenib Sensitive : A2
BRAF V600	Melanoma	BRAF V600	Melanoma	trametinib + dabrafenib + PDR001 Sensitive: B - Late Trials trametinib + dabrafenib + PDR001 Sensitive : B	trametinib + dabrafenib + PDR001 Sensitive: B - Late Trials trametinib + dabrafenib + PDR001 Sensitive : B
BRAF V600	Melanoma	BRAF V600	Melanoma	nivolumab + ipilimumab Sensitive: B - Late Trials nivolumab + ipilimumab Sensitive : B	nivolumab + ipilimumab Sensitive: B - Late Trials nivolumab + ipilimumab Sensitive : B
BRAF V600	Melanoma	BRAF V600	Melanoma	PD1 inhibitor Sensitive: B - Late Trials PD1 inhibitor Sensitive : B	PD1 inhibitor Sensitive: B - Late Trials PD1 inhibitor Sensitive : B
BRAF V600	Thyroid Gland Carcinoma	BRAF V600	Thyroid Gland Carcinoma	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1
BRAF V600	Ocular Melanoma	BRAF V600	Ocular Melanoma	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1
BRAF V600	Ocular Melanoma	BRAF V600	Ocular Melanoma	trametinib + dabrafenib Sensitive: C1 - Off-label trametinib + dabrafenib Sensitive : C1	trametinib + dabrafenib Sensitive: C1 - Off-label trametinib + dabrafenib Sensitive : C1
BRAF V600	Multiple Myeloma	BRAF V600	Multiple Myeloma	binimetinib + encorafenib Sensitive: C1 - Off-label binimetinib + encorafenib Sensitive : C1	binimetinib + encorafenib Sensitive: C1 - Off-label binimetinib + encorafenib Sensitive : C1
BRAF V600	Colorectal Cancer	BRAF V600	Colorectal Cancer	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1
BRAF V600	Cholangiocarcinoma	BRAF V600	Cholangiocarcinoma	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1
BRAF V600	Ganglioglioma	BRAF V600	Ganglioglioma	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1	vemurafenib Sensitive: C1 - Off-label vemurafenib Sensitive : C1

BRAF V600

Associations