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DRUG:

icovamenib (BMF-219)

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Company:

Biomea Fusion

Drug class:

Menin-MLL inhibitor

Related drugs:

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KRAS G12V	Pancreatic Cancer	KRAS G12V	Pancreatic Cancer	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
KRAS G12D	Non Small Cell Lung Cancer	KRAS G12D	Non Small Cell Lung Cancer	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
KRAS G12C	Colorectal Cancer	KRAS G12C	Colorectal Cancer	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
KRAS G12C	Lung Cancer	KRAS G12C	Lung Cancer	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
Chr del(13q)	Chronic Lymphocytic Leukemia	Chr del(13q)	Chronic Lymphocytic Leukemia	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
NOTCH1 mutation	Chronic Lymphocytic Leukemia	NOTCH1 mutation	Chronic Lymphocytic Leukemia	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
TP53 mutation	Chronic Lymphocytic Leukemia	TP53 mutation	Chronic Lymphocytic Leukemia	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
NRAS mutation	Multiple Myeloma	NRAS mutation	Multiple Myeloma	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
KRAS mutation	Multiple Myeloma	KRAS mutation	Multiple Myeloma	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D
TP53 mutation	Multiple Myeloma	TP53 mutation	Multiple Myeloma	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D	BMF-219 Sensitive: D – Preclinical BMF-219 Sensitive : D