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BIOMARKER:

BCR-ABL1 Y253F

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Entrez ID:

Related biomarkers:

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BCR-ABL1 fusion (70)

BCR-ABL1 T315I (32)

BCR-ABL1 E255K (10)

BCR-ABL1 V299L (10)

BCR-ABL1 F317L (8)

BCR-ABL1 Y253H (8)

BCR-ABL1 E255V (6)

BCR-ABL1 F359C (6)

BCR-ABL1 G250E (6)

BCR-ABL1 M244V (6)

BCR-ABL1 D276G (5)

BCR-ABL1 F359V (5)

BCR-ABL1 L248V (5)

BCR-ABL1 M351T (5)

BCR-ABL1 E279K (4)

BCR-ABL1 G398R (4)

BCR-ABL1 H396P (4)

BCR-ABL1 H396R (4)

BCR-ABL1 L384M (4)

BCR-ABL1 Q252H (4)

BCR-ABL1 V379I (4)

SNX2-ABL1 fusion (4)

BCR-ABL1 F317V (3)

BCR-ABL1 F359I (3)

BCR-ABL1 F486S (3)

BCR-ABL1 mutation (3)

NUP214-ABL1 fusion (3)

BCR-ABL1 A397P (2)

BCR-ABL1 E355G (2)

BCR-ABL1 E459K (2)

BCR-ABL1 F317C (2)

BCR-ABL1 F317I (2)

BCR-ABL1 L387M (2)

BCR-ABL1 T315A (2)

BCR-FGFR1 fusion (2)

ABL1 fusion (1)

BCR exon 13-ABL1 exon 3 fusion (1)

BCR-ABL1 C475V (1)

BCR-ABL1 D363G (1)

BCR-ABL1 D444G (1)

BCR-ABL1 E292V (1)

BCR-ABL1 E355G + BCR-ABL1 Q252R (1)

BCR-ABL1 E450G (1)

BCR-ABL1 E450Q (1)

BCR-ABL1 E453A (1)

BCR-ABL1 E98G (1)

BCR-ABL1 F311I (1)

BCR-ABL1 F311V (1)

BCR-ABL1 F359 (1)

BCR-ABL1 F3llL (1)

BCR-ABL1 G250E + BCR-ABL1 F317L (1)

BCR-ABL1 I403T (1)

BCR-ABL1 I403V (1)

BCR-ABL1 I432T (1)

BCR-ABL1 L248R (1)

BCR-ABL1 L323P (1)

BCR-ABL1 L364I (1)

BCR-ABL1 L387F (1)

BCR-ABL1 M388L (1)

BCR-ABL1 M388L + BCR-ABL1 M244V (1)

BCR-ABL1 N336S (1)

BCR-ABL1 N49S (1)

BCR-ABL1 Q252R (1)

BCR-ABL1 Q255K (1)

BCR-ABL1 Q300R (1)

BCR-ABL1 S417T (1)

BCR-ABL1 S417Y (1)

BCR-ABL1 T315M (1)

BCR-ABL1 V229L (1)

BCR-ABL1 V289A (1)

BCR-ABL1 V289I (1)

Chr t(3;9)(p13;q34) FOXP1/ABL1 (1)

ETV6-ABL1 fusion (1)

FOXP1-ABL1 Fusion (1)

INPP5D-ABL1 fusion (1)

BCR exon 1-PDGFRA exon 13 fusion (1)

BCR-JAK2 fusion (1)

ABL1-RCSD1 fusion (0)

BCR-ABL1 V289I + BCR-ABL1 M388L (0)

BCR-ABL1 V338G (0)

BCR-ABL1 fusion negative (0)

JAK2-ABL1 fusion (0)

BCR-ABL1 fusion (70)

BCR-ABL1 T315I (32)

BCR-ABL1 E255K (10)

BCR-ABL1 V299L (10)

BCR-ABL1 F317L (8)

BCR-ABL1 Y253H (8)

BCR-ABL1 E255V (6)

BCR-ABL1 F359C (6)

BCR-ABL1 G250E (6)

BCR-ABL1 M244V (6)

BCR-ABL1 D276G (5)

BCR-ABL1 F359V (5)

BCR-ABL1 L248V (5)

BCR-ABL1 M351T (5)

BCR-ABL1 E279K (4)

BCR-ABL1 G398R (4)

BCR-ABL1 H396P (4)

BCR-ABL1 H396R (4)

BCR-ABL1 L384M (4)

BCR-ABL1 Q252H (4)

BCR-ABL1 V379I (4)

SNX2-ABL1 fusion (4)

BCR-ABL1 F317V (3)

BCR-ABL1 F359I (3)

BCR-ABL1 F486S (3)

BCR-ABL1 mutation (3)

NUP214-ABL1 fusion (3)

BCR-ABL1 A397P (2)

BCR-ABL1 E355G (2)

BCR-ABL1 E459K (2)

BCR-ABL1 F317C (2)

BCR-ABL1 F317I (2)

BCR-ABL1 L387M (2)

BCR-ABL1 T315A (2)

BCR-FGFR1 fusion (2)

ABL1 fusion (1)

BCR exon 13-ABL1 exon 3 fusion (1)

BCR-ABL1 C475V (1)

BCR-ABL1 D363G (1)

BCR-ABL1 D444G (1)

BCR-ABL1 E292V (1)

BCR-ABL1 E355G + BCR-ABL1 Q252R (1)

BCR-ABL1 E450G (1)

BCR-ABL1 E450Q (1)

BCR-ABL1 E453A (1)

BCR-ABL1 E98G (1)

BCR-ABL1 F311I (1)

BCR-ABL1 F311V (1)

BCR-ABL1 F359 (1)

BCR-ABL1 F3llL (1)

BCR-ABL1 G250E + BCR-ABL1 F317L (1)

BCR-ABL1 I403T (1)

BCR-ABL1 I403V (1)

BCR-ABL1 I432T (1)

BCR-ABL1 L248R (1)

BCR-ABL1 L323P (1)

BCR-ABL1 L364I (1)

BCR-ABL1 L387F (1)

BCR-ABL1 M388L (1)

BCR-ABL1 M388L + BCR-ABL1 M244V (1)

BCR-ABL1 N336S (1)

BCR-ABL1 N49S (1)

BCR-ABL1 Q252R (1)

BCR-ABL1 Q255K (1)

BCR-ABL1 Q300R (1)

BCR-ABL1 S417T (1)

BCR-ABL1 S417Y (1)

BCR-ABL1 T315M (1)

BCR-ABL1 V229L (1)

BCR-ABL1 V289A (1)

BCR-ABL1 V289I (1)

Chr t(3;9)(p13;q34) FOXP1/ABL1 (1)

ETV6-ABL1 fusion (1)

FOXP1-ABL1 Fusion (1)

INPP5D-ABL1 fusion (1)

BCR exon 1-PDGFRA exon 13 fusion (1)

BCR-JAK2 fusion (1)

ABL1-RCSD1 fusion (0)

BCR-ABL1 V289I + BCR-ABL1 M388L (0)

BCR-ABL1 V338G (0)

BCR-ABL1 fusion negative (0)

JAK2-ABL1 fusion (0)

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BCR-ABL1 Y253F	Chronic Myeloid Leukemia	BCR-ABL1 Y253F	Chronic Myeloid Leukemia	imatinib Sensitive: C3 – Early Trials imatinib Sensitive : C3	imatinib Sensitive: C3 – Early Trials imatinib Sensitive : C3
BCR-ABL1 Y253F	Chronic Myeloid Leukemia	BCR-ABL1 Y253F	Chronic Myeloid Leukemia	bosutinib Sensitive: D – Preclinical bosutinib Sensitive : D	bosutinib Sensitive: D – Preclinical bosutinib Sensitive : D
BCR-ABL1 Y253F	Chronic Myeloid Leukemia	BCR-ABL1 Y253F	Chronic Myeloid Leukemia	nilotinib Sensitive: D – Preclinical nilotinib Sensitive : D	nilotinib Sensitive: D – Preclinical nilotinib Sensitive : D
BCR-ABL1 Y253F	Chronic Myeloid Leukemia	BCR-ABL1 Y253F	Chronic Myeloid Leukemia	dasatinib Sensitive: D – Preclinical dasatinib Sensitive : D	dasatinib Sensitive: D – Preclinical dasatinib Sensitive : D