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BIOMARKER:

BCR-ABL1 Y253H

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Other names: BCR, BCR Activator Of RhoGEF And GTPase, BCR, RhoGEF And GTPase Activating Protein, Breakpoint Cluster Region Protein, Renal Carcinoma Antigen NY-REN-26, Breakpoint Cluster Region, D22S11, BCR1, BCR/FGFR1 Chimera Protein, FGFR1/BCR Chimera Protein, D22S662, ALL, CML, PHL, ABL proto-oncogene 1, ABL, c-ABL, JTK7, p150, ABL1
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Entrez ID:
BCR-ABL1 Y253H
Chronic Myeloid Leukemia
nilotinib
Resistant
:
A2
BCR-ABL1 Y253H
Acute Lymphocytic Leukemia
nilotinib
Resistant
:
A2
BCR-ABL1 Y253H
Chronic Myeloid Leukemia
dasatinib
Sensitive
:
B
BCR-ABL1 Y253H
Chronic Myeloid Leukemia
bosutinib
Sensitive
:
C3
BCR-ABL1 Y253H
Acute Lymphocytic Leukemia
dasatinib
Sensitive
:
C3
BCR-ABL1 Y253H
Chronic Myeloid Leukemia
imatinib
Resistant
:
C3
BCR-ABL1 Y253H
Chronic Myeloid Leukemia
CUDC-907
Sensitive
:
D
BCR-ABL1 Y253H
Chronic Myeloid Leukemia
imatinib + nilotinib
Resistant
:
D