CANCER:

Ampulla of Vater Carcinoma

KRAS G12C KRAS G12C	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	KRAS G12C KRAS G12C	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	sotorasib Sensitive: C1 - Off-label	sotorasib Sensitive: C1 - Off-label
MUC2 negative MUC2 negative	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	MUC2 negative MUC2 negative	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	gemcitabine Resistant: C3 – Early Trials	gemcitabine Resistant: C3 – Early Trials
KRT7 expression KRT7 expression	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	KRT7 expression KRT7 expression	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	gemcitabine Resistant: C3 – Early Trials	gemcitabine Resistant: C3 – Early Trials
KRT7 expression KRT7 expression	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	KRT7 expression KRT7 expression	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	cisplatin + gemcitabine + albumin-bound paclitaxel Sensitive: C3 – Early Trials	cisplatin + gemcitabine + albumin-bound paclitaxel Sensitive: C3 – Early Trials
KRT7 expression + MUC1 expression KRT7 expression + MUC1 expression	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	KRT7 expression + MUC1 expression KRT7 expression + MUC1 expression	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	gemcitabine + albumin-bound paclitaxel Sensitive: C3 – Early Trials	gemcitabine + albumin-bound paclitaxel Sensitive: C3 – Early Trials
HER-2 mutation + CDK6 mutation HER-2 mutation + CDK6 mutation	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	HER-2 mutation + CDK6 mutation HER-2 mutation + CDK6 mutation	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	palbociclib + pertuzumab + ribociclib + abemaciclib + trastuzumab/hyaluronidase-oysk Sensitive: C3 – Early Trials	palbociclib + pertuzumab + ribociclib + abemaciclib + trastuzumab/hyaluronidase-oysk Sensitive: C3 – Early Trials
BRAF D594G BRAF D594G	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	BRAF D594G BRAF D594G	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	encorafenib + binimetinib Sensitive: C3 – Early Trials	encorafenib + binimetinib Sensitive: C3 – Early Trials
PIK3CA mutation PIK3CA mutation	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	PIK3CA mutation PIK3CA mutation	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	everolimus Sensitive: C4 – Case Studies	everolimus Sensitive: C4 – Case Studies
NRAS mutation + BRAF mutation NRAS mutation + BRAF mutation	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	NRAS mutation + BRAF mutation NRAS mutation + BRAF mutation	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	MEK inhibitor Sensitive: C4 – Case Studies	MEK inhibitor Sensitive: C4 – Case Studies
HER-2 G660D + HER-2 S310F HER-2 G660D + HER-2 S310F	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	HER-2 G660D + HER-2 S310F HER-2 G660D + HER-2 S310F	Ampulla of Vater Carcinoma Ampulla of Vater Carcinoma	afatinib Sensitive: C4 – Case Studies	afatinib Sensitive: C4 – Case Studies