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BIOMARKER:
FGFR2 amplification
i
Other names:
FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor 2
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Entrez ID:
2263
Related biomarkers:
Expression
Mutation
Fusion
Others
‹
FGFR2 mutation (30)
FGFR2 N549K (7)
FGFR2 rearrangement (7)
FGFR2 P253R (3)
FGFR2 K310R (2)
FGFR2 translocation (2)
ARID1A K1238fs + FGFR2 R210Q (1)
BAP1 mutation + FGFR2 rearrangement (1)
FDFT1 rearrangement + FGFR2 rearrangement (1)
FGFR2 A391E (1)
FGFR2 B252W (1)
FGFR2 C382R (1)
FGFR2 E250G (1)
FGFR2 E565A (1)
FGFR2 E565G (1)
FGFR2 E565K (1)
FGFR2 F276C (1)
FGFR2 M540_I541insMM (1)
FGFR2 N549D (1)
FGFR2 N549H (1)
FGFR2 N549T (1)
FGFR2 N550K (1)
FGFR2 S252W (1)
FGFR2 V564F (1)
FGFR2 V564I (1)
FGFR2 V564L (1)
FGFR2 Y375C (1)
FGFR2 Y376C (1)
PIK3CA mutation + FGFR2 rearrangement (1)
PIK3CB mutation + FGFR2 rearrangement (1)
PIK3R1 mutation + FGFR2 rearrangement (1)
TP53 mutation + FGFR2 rearrangement (1)
FGFR2 C383R (0)
FGFR2 K660N (0)
FGFR2 W290C (0)
FGFR2 wild-type (0)
FGFR2 mutation (30)
FGFR2 N549K (7)
FGFR2 rearrangement (7)
FGFR2 P253R (3)
FGFR2 K310R (2)
FGFR2 translocation (2)
ARID1A K1238fs + FGFR2 R210Q (1)
BAP1 mutation + FGFR2 rearrangement (1)
FDFT1 rearrangement + FGFR2 rearrangement (1)
FGFR2 A391E (1)
FGFR2 B252W (1)
FGFR2 C382R (1)
FGFR2 E250G (1)
FGFR2 E565A (1)
FGFR2 E565G (1)
FGFR2 E565K (1)
FGFR2 F276C (1)
FGFR2 M540_I541insMM (1)
FGFR2 N549D (1)
FGFR2 N549H (1)
FGFR2 N549T (1)
FGFR2 N550K (1)
FGFR2 S252W (1)
FGFR2 V564F (1)
FGFR2 V564I (1)
FGFR2 V564L (1)
FGFR2 Y375C (1)
FGFR2 Y376C (1)
PIK3CA mutation + FGFR2 rearrangement (1)
PIK3CB mutation + FGFR2 rearrangement (1)
PIK3R1 mutation + FGFR2 rearrangement (1)
TP53 mutation + FGFR2 rearrangement (1)
FGFR2 C383R (0)
FGFR2 K660N (0)
FGFR2 W290C (0)
FGFR2 wild-type (0)
›
Associations
(23)
News
Trials
Search handles
@aftimosp
@carlosbon78
Search handles
@aftimosp
@carlosbon78
Filter by
Latest
10ms
Open label phase-2 trial of Futibatinib in advanced gastric cancer with FGFR2 amplification and at least two prior systemic regimens for advanced/metastatic disease. Modest results: ORR 17.9%, DCR 50%, mDoR 3.9 m, mPFS 2.8 m, mOS 5.7 months #WCGIC2023 (@carlosbon78)
10 months ago
Clinical • P2 data • Metastases
|
FGFR2 (Fibroblast growth factor receptor 2)
|
FGFR2 amplification
|
Lytgobi (futibatinib)
over2years
The national molecular tumor board of the @mybsmo GeNeo and BALLETT molecular screening programs allows us to identify patients all over Belgium 🇧🇪with FGFR rearrangements or FGFR2 amplification (only gastric cancer in this cohort) for the phase 2 study https://t.co/TJ7QlxoGOx (@aftimosp)
over 2 years ago
Clinical
|
FGFR2 (Fibroblast growth factor receptor 2)
|
FGFR2 amplification • FGFR2 rearrangement
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