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BIOMARKER:
FGFR2 amplification
i
Other names:
FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor 2
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Entrez ID:
2263
Related biomarkers:
Expression
Mutation
Fusion
Others
‹
BAP1 mutation + FGFR2 fusion (1)
FGFR2 underexpression + FGFR3 mutation (1)
IDH1 mutation + FGFR2 fusion (1)
IDH1 mutation + FGFR2 rearrangement (1)
NOTCH1 positive + FGFR2 mutation (1)
PBRM1 mutation + FGFR2 fusion (1)
TP53 mutation + FGFR2 fusion (1)
FGFR2 K660N + TP53 deletion (0)
BAP1 mutation + FGFR2 fusion (1)
FGFR2 underexpression + FGFR3 mutation (1)
IDH1 mutation + FGFR2 fusion (1)
IDH1 mutation + FGFR2 rearrangement (1)
NOTCH1 positive + FGFR2 mutation (1)
PBRM1 mutation + FGFR2 fusion (1)
TP53 mutation + FGFR2 fusion (1)
FGFR2 K660N + TP53 deletion (0)
›
Associations
(23)
News
Trials
Search handles
@aftimosp
@carlosbon78
Search handles
@aftimosp
@carlosbon78
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Latest
10ms
Open label phase-2 trial of Futibatinib in advanced gastric cancer with FGFR2 amplification and at least two prior systemic regimens for advanced/metastatic disease. Modest results: ORR 17.9%, DCR 50%, mDoR 3.9 m, mPFS 2.8 m, mOS 5.7 months #WCGIC2023 (@carlosbon78)
10 months ago
Clinical • P2 data • Metastases
|
FGFR2 (Fibroblast growth factor receptor 2)
|
FGFR2 amplification
|
Lytgobi (futibatinib)
over2years
The national molecular tumor board of the @mybsmo GeNeo and BALLETT molecular screening programs allows us to identify patients all over Belgium 🇧🇪with FGFR rearrangements or FGFR2 amplification (only gastric cancer in this cohort) for the phase 2 study https://t.co/TJ7QlxoGOx (@aftimosp)
over 2 years ago
Clinical
|
FGFR2 (Fibroblast growth factor receptor 2)
|
FGFR2 amplification • FGFR2 rearrangement
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