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Validation of Dual-Color Dual In Situ Hybridization for HER2/neu Gene in Breast Cancer. (PubMed, Arch Pathol Lab Med)
"We successfully validated the latest version of D-DISH assay as a substitute for FISH in predicting HER2 gene status with significant interobserver reproducibility, concluding that this D-DISH assay may be introduced in routine diagnostic services as a reflex test to ascertain HER2 gene status."
Journal
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HER-2 (Human epidermal growth factor receptor 2)
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HER-2 amplification
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PATHWAY antiHer2/neu (4B5) Rabbit Monoclonal Primary Antibody • VENTANA HER2 Dual ISH DNA Probe Cocktail • ZytoLight® SPEC ERBB2/CEN 17 Dual Color Probe Kit
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Herceptin (trastuzumab)