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    The ZytoLight ® SPEC ROS1 Dual Color Break Apart Probe is designed to detect translocations involving the chromosomal region 6q22.1 harboring the ROS proto-oncogene 1, receptor tyrosine kinase (ROS1, a.k.a. MCF3) gene. Translocations affecting ROS1 have been detected in various tumors including non-small cell lung cancer (NSCLC). Administration of ROS1 kinase inhibitors may represent a very effective therapeutic strategy in NSCLC patients harboring activating ROS1 rearrangements.
    Cancer:
    Non Small Cell Lung Cancer
    Gene:
    ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS)
    Method:
    Fluorescence in situ hybridization (FISH)