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U-TOP MSI detection kit

U-TOP MSI detection kit is a product that diagnoses MSI, which is essential for selective administration of immune anticancer drugs (immune checkpoint inhibitors) such as 'Keytruda' (active ingredient pembrolizumab). MSI is a phenomenon in which mutations accumulate due to the failure of the DNA mismatch repair gene (dMMR gene) function to properly complement bases mistakenly created during DNA replication. It has been observed in various solid cancers such as colorectal cancer, stomach cancer, endometrial cancer, ovarian cancer, pancreatic cancer, biliary tract cancer, lung cancer, bladder cancer, and prostate cancer, so it has a wide range of uses as a diagnostic indicator.