In, conclusion, investigating the three selected pathogenic mutations showed a clear impact on the structure of the protein favored different types of bonds in the active site that may alter the interaction between BRCA1 and BARD1. This study has a beneficial role to investigate the impact of BRCA1 mutations on the structural stability of the protein and thereby the risk of BC development
over 1 year ago
Clinical • BRCA Biomarker
|
BRCA1 (Breast cancer 1, early onset) • BRCA (Breast cancer early onset) • BARD1 (BRCA1 Associated RING Domain 1)
"Shuwen Biotech...today announces that it has entered into a distribution agreement with Devyser Diagnostics...to market and support Devyser BRCA NGS and other oncology kits in China. Under the terms of the agreement, Shuwen will distribute the Devyser kits in China and also offer testing and NGS data analysis services with the Devyser kits in its CAP-accredited clinical labs in China."
Results suggested possible risk factors associated with the presence of both oncogenic viruses and BRCA mutations, which might in turn affected management of BC disease, but larger sample size is still needed to evaluate such a correlation.
almost 3 years ago
Clinical • BRCA Biomarker
|
BRCA1 (Breast cancer 1, early onset) • BRCA2 (Breast cancer 2, early onset) • BRCA (Breast cancer early onset)