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Company:
DevyserType:
Laboratory Developed Test
Related tests:
Devyser LynchFAP provides a comprehensive solution to analyze PMS2 and 9 other genes associated with hereditary colorectal cancer syndromes. Devyser LynchFAP is designed to overcome one of the greatest challenges for Lynch syndrome genetic testing - the localization of genetic variants to PMS2 and its pseudogene PMS2CL. Devyser LynchFAP is the first commercial library prep kit to allow this specific analysis of the PMS2 gene.
Cancer:
Colon Cancer, Colorectal Cancer
Gene:
APC (APC Regulator Of WNT Signaling Pathway), CTNNB1 (Catenin (cadherin-associated protein), beta 1), EPCAM (Epithelial cell adhesion molecule), MLH1 (MutL homolog 1), MSH2 (MutS Homolog 2), MSH6 (MutS homolog 6)
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APC (APC Regulator Of WNT Signaling Pathway), CTNNB1 (Catenin (cadherin-associated protein), beta 1), EPCAM (Epithelial cell adhesion molecule), MLH1 (MutL homolog 1), MSH2 (MutS Homolog 2), MSH6 (MutS homolog 6), MUTYH (MutY homolog), PMS2 (PMS1 protein homolog 2), POLD1 (DNA Polymerase Delta 1), POLE (DNA Polymerase Epsilon)
Method:
Next-Generation Sequencing (NGS)
