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    TEST:
    DecisionDx®-UMSeq

    Company:
    Castle Biosci
    Type:
    Laboratory Developed Test
    Related tests:

    Details

    Evidence
    News
    The DecisionDx-UMSeq test is a 7-gene panel that uses next-generation sequencing (NGS) to identify somatic mutations relevant to UM. The test includes hotspot mutations in the genes GNAQ, GNA11, CYSLTR2, PLCB4, and SF3B1, mutations in exons 1-2 of EIF1AX, and all coding exons of the BAP1 gene.
    Cancer:
    Uveal Melanoma
    Gene:
    BAP1 (BRCA1 Associated Protein 1), CYSLTR2 (Cysteinyl Leukotriene Receptor 2), GNA11 (G Protein Subunit Alpha 11), GNAQ (G Protein Subunit Alpha Q), PLCB4 (Phospholipase C Beta 4), SF3B1 (Splicing Factor 3b Subunit 1)
    Method:
    Next-Generation Sequencing (NGS)