Preclinical • Journal • Combination therapy
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KRAS (KRAS proto-oncogene GTPase) • BRAF (B-raf proto-oncogene) • NRAS (Neuroblastoma RAS viral oncogene homolog) • ADRB2 (Adrenoceptor Beta 2) • PRKDC (Protein Kinase, DNA-Activated, Catalytic Subunit) • PTK2B (Protein Tyrosine Kinase 2 Beta)
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KRAS mutation • BRAF mutation • KRAS wild-type • RAS wild-type
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avutometinib (VS-6766) • defactinib (VS-6063) • VS-4718