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    DRUG:

    saridegib oral (IPI 926 oral)

    i
    Other names: IPI 926 oral
    Company:
    Infinity Pharma, Mundipharma
    Drug class:
    Hedgehog cell-signalling pathway inhibitor, SMO protein inhibitor
    Related drugs:
    5d
    Phase 2 Trial of Topical Application of the Hedgehog Inhibitor Patidegib in Patients With Gorlin Syndrome. (PubMed, Br J Dermatol)
    Patidegib Topical Gel warrants further clinical development.
    P2 data • Journal
    |
    PTCH1 (Patched 1)
    |
    PTCH1 mutation
    |
    cyclopamine • saridegib oral (IPI 926 oral) • patidegib topical (IPI-926 topical)