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    DRUG:

    Riabni (rituximab-arrx)

    i
    Other names: ABP 798 , ABP798, ABP-798
    Company:
    AbbVie, Amgen
    Drug class:
    CD20 inhibitor
    Related drugs:
    4years
    Rituximab, Pembrolizumab, and Obinutuzumab in Treating Patients With Relapsed or Refractory Follicular Lymphoma or Diffuse Large B Cell Lymphoma (clinicaltrials.gov)
    N=37 --> 62
    Clinical • Enrollment change • PD(L)-1 Biomarker
    |
    CD20 (Membrane Spanning 4-Domains A1)
    |
    Keytruda (pembrolizumab) • Rituxan (rituximab) • Gazyva (obinutuzumab) • Riabni (rituximab-arrx) • Delito (rituximab biosimilar) • GB241 (rituximab biosimilar) • Novex (rituximab biosimilar)
    4years
    Efficacy and Safety of ABP 798: Results from the JASMINE Trial in Patients with Follicular Lymphoma in Comparison with Rituximab Reference Product. (PubMed, Target Oncol)
    These results support a conclusion of similar clinical efficacy between ABP 798 and rituximab RP in patients with follicular lymphoma.
    Clinical • Journal
    |
    CD19 (CD19 Molecule)
    |
    Riabni (rituximab-arrx)
    4years
    Rituximab, Pembrolizumab, and Obinutuzumab in Treating Patients With Relapsed or Refractory Follicular Lymphoma or Diffuse Large B Cell Lymphoma (clinicaltrials.gov)
    Trial completion date: Feb 2021 --> Feb 2023 | Trial primary completion date: Feb 2021 --> Feb 2023
    Clinical • Trial completion date • Trial primary completion date • PD(L)-1 Biomarker
    |
    CD20 (Membrane Spanning 4-Domains A1)
    |
    Keytruda (pembrolizumab) • Rituxan (rituximab) • Gazyva (obinutuzumab) • Riabni (rituximab-arrx) • Delito (rituximab biosimilar) • GB241 (rituximab biosimilar) • Novex (rituximab biosimilar)
    5years
    A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma (clinicaltrials.gov)
    P2; Not yet recruiting --> Recruiting
    Enrollment open • Clinical
    |
    CCND1 (Cyclin D1) • CD34 (CD34 molecule)
    |
    CCND1 expression
    |
    clonoSEQ
    |
    Rituxan (rituximab) • cytarabine • Calquence (acalabrutinib) • bendamustine • Belrapzo (bendamustine RTD) • Riabni (rituximab-arrx) • Delito (rituximab biosimilar) • GB241 (rituximab biosimilar) • JHL1101 (rituximab biosimilar) • Novex (rituximab biosimilar)
    5years
    A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma (clinicaltrials.gov)
    P2; N=369; Not yet recruiting; Sponsor:ECOG-ACRIN Cancer Research Group
    New P2 trial • Clinical
    |
    CCND1 (Cyclin D1) • CD34 (CD34 molecule)
    |
    CCND1 expression
    |
    clonoSEQ
    |
    Rituxan (rituximab) • cytarabine • Calquence (acalabrutinib) • bendamustine • Belrapzo (bendamustine RTD) • Riabni (rituximab-arrx) • Delito (rituximab biosimilar) • GB241 (rituximab biosimilar) • JHL1101 (rituximab biosimilar) • Novex (rituximab biosimilar)